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By Target- Autophagy
- FXR(1)
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Results for "
int 747
" in TargetMol Product Catalog- Inhibitors & Agonists1
Obeticholic Acid
INT-747,6-Ethylchenodeoxycholic acid,6-ECDCA
T1789459789-99-2
Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist with an EC50 of 99 nM and is able to upregulate IκB-α, KLF-2, and KLF-4 expression. Obeticholic Acid (6-ECDCA, INT-747) also shows potential for treating hepatic steatosis, inflammation, and fibrosis while increasing insulin sensitivity.
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