iwp o1

IWP-O1, a highly potent Porcupine (Porcn) inhibitor (EC50: 80 pM), effectively suppresses the phosphorylation of Dvl2 3 and LRP6 in HeLa cells.

6-(4-methylpiperazin-1-yl)-4-o-tolylnicotinamide can be used in the synthesis of befetupitant and netupitant.

Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside is a natural peoduct isolated from Arabian jasmine

1-O-Hexadecyl-Rac-Glycerol (1-O-Hexadecylglycerol) is a marine derived natural products found in Tritoniella belli.

(2S)-1-O-p-coumaroyl-2-O-acetyl-3-O-β-D-glucopyranosylglycerol is a useful research compound for many research applications, including the fields of chemistry and life sciences, among others.

(25R)-3β,17α-dihydroxy-5α- spirostan-6-one3-O-α-L- rhamnopyranosyl-(1→2)-β- D-glucopyranoside is a natural product isolated from the bulbs of Lilium brownii var. viridulum.

1-Acetyl-3-o-toluyl-5-fluorouracil is a potent antineoplastic agent.

(-)-Syringaresnol-4-O-β-D-apiofuranosyl-(1→2)-β-D-glucopyranoside ((-)-Syringaresnol-4-O-beta-D-apiofuranos) is a lignan glycoside derived from the bark of Albizzia myriophylla.

1. Emodin-1-O-β-D-glucopyranoside (Emodin-1-O-glucoside) has neuroprotective and uncoupling activities, and that it may be the a new uncoupler of nNOS-PSD-95. 2. Emodin-1-O-β-D-glucopyranoside shows inhibitory effects on various tumor cells proliferation.

Quercetin 3-O-Glc-(1→2)-Rha-7-O-Rha is a flavonol glycoside with no significant inhibitory effects on lipid accumulation induced by albumin oleate.

Hederagenin 28-O-{β-D-xylopyranosyl-(1→6)-β-D-glucopyranosyl ester}3-O-{α-L-rhamnopyranosyl-(1→2)-α-L-arabinopyranosyl} is a saponin known for its antitumor and anti-inflammatory properties [1].

Rp-Uridine-5'-O-(1-thiotriphosphate) (Rp-UTP-α-S) serves as a nucleotide agonist for purinergic P2Y2 and P2Y4 receptors, effectively inducing inositol phosphate accumulation within 1321N1 astrocytoma cells that express either P2Y2 or P2Y4 receptors, with EC50 values of 5.4 and 27 µM, respectively.

1-(3',5'-dimethoxy)phenyl-2-[4''-O-β-D-glucopyranosyl (6→1)-O-α-L-rhamnopyranosyl]phenylethane showed cytotoxic activities to Hela and hep2 cell lines.

(Met(O)35)-Amyloid β-Protein (1-42) is the oxidized form of Methionine 35 in Aβ42, capable of producing an oligomer size distribution similar to Aβ40. This compound is utilized in Alzheimer’s disease (AD) research [1].

Benzyl [5-O-benzoyl-β-D-apiofuranosyl(1→2)]-β-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN5741 and the CAS number is 1097040-08-8.

Kaempferol-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside exhibits antioxidant activity.

1-O-Methylemodin, a natural product isolated from Zopfiella longicaudata, exhibits antifungal activity [1].

Rp-2'-Deoxyuridine-5'-O-(1-thiotriphosphate) (Rp-dUTP-α-S), a sulfur-containing nucleotide isomer and purinergic P2Y2 receptor agonist, preferentially promotes inositol phosphate accumulation in 1321N1 astrocytoma cells with P2Y2 receptors (EC50 = 12.5 µM) compared to those expressing P2Y4 receptors at a concentration of 10 µM.

Sp-2'-Deoxycytidine-5'-O-(1-thiotriphosphate) (Sp-dCTP-α-S), an isomer of the sulfur-containing nucleotide derivative dCTP-α-S, functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an inhibition constant (Ki) of 6.3 µM.

1-O-Hexadecyl-2-eicosapentaenoyl-sn-glycero-3-PC is a compound that results from the incorporation of eicosapentaenoic acid (EPA) into lyso-PAF C-16, a process demonstrated in neutrophils from monkeys and humans consuming a diet rich in fish oils. Furthermore, it functions as a precursor for PAF C-16 synthesis via the remodeling pathway.

1-O-Caffeoyl-3-O-galloyl-4,6-(S)-hexahydroxydiphen is a useful organic compound for research related to life sciences. The catalog number is T124953 and the CAS number is 359828-21-0.

N4-Benzoyl-1-(6-O-DMTr-2,3-dideoxy-beta-D-erythro-hexopyranosyl)cytosine is a useful organic compound for research related to life sciences. The catalog number is TNU1623 and the CAS number is 145594-00-9.

1-[3’-O-[(4,4’-dimethoxytriphenyl)methyl]-a-L-threofuranosyl]-N6-benzoyladenine is a useful organic compound for research related to life sciences. The catalog number is TNU1629 and the CAS number is 325683-88-3.

Borneol 7-O-[beta-D-apiofuranosyl-(1->6)]-beta-D-glucopyranoside is a natural product from Radix ophiopogonis.

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a useful organic compound for research related to life sciences and the catalog number is T67406.

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin 3-O-beta-(6''-p-coumaroyl)glucopyranosyl(1->2)-alpha-L-rhamnopyranoside) is a compound extracted from the leaves of Ginkgo biloba with notable antioxidant properties.

1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.

1,3,6-Trihydroxy-2-methylanthraquinone 3-O-alpha-L-rhamnosyl-(1->2)-beta-D-glucoside is a natural product

Ophiogenin 3-O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside (Ophiogenin-3-O-alpha-L-rhaMnopyranosyl-(1->2)-beta-D-glucopyranoside) is a natural product with significant pharmacological effects on the cardiovascular system.

4-Hydroxy-3-methoxyphenol 1-O-(6-O-syringoyl)glucoside is a useful organic compound for research related to life sciences and the catalog number is T124850.

1-[6-Phosphono-2-O-methyl-β-D-ribo-hexofuranosyl]uracil is a nucleoside derivative and phosphorus-containing nucleotide, with both 2'- and 5'-modifications.

Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][[5-[(dimethylamino)sulfonyl]-2-(1-methylethoxy-O)phenyl]methylene-C]ruthenium(II) is a useful organic compound for research related to life sciences and the catalog number is T66135.

1-[(5E)-3-O-[(Bis-di-isopropyl amino)(2-cyanoethoxy) phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is a Nucleoside Phosphoramidite; Nucleoside Derivative - Phosphorus-containing nucleotide; 5'-Modified nucleoside.

1-O-Caffeoylglucose is a useful organic compound for research related to life sciences and the catalog number is T125866.

Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside derived from the seeds of Cassia obtusifolia, specifically inhibits hMAO-A isozyme activity with an IC50 value of 96.15 μM.

1-O-(4,4'-Dimethoxytrityl)-3-O-succinyl-l,3-propanediol is a Fine Chemical.

1-(3’-O-[4,4’-dimethoxytrityl]-alpha-L-threofuranosyl)uridine, catalog number TNU1627 and CAS number 325683-90-7, is a valuable organic compound for life sciences research.

1,4-Dihydroxy-2-carbomethoxy-3-prenylnaphthalene-1-O-beta-glucopyranoside may exhibit inhibitory activity against DNA topoisomerases I and II and demonstrate cytotoxicity.

2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside commonly found in the bulbs of [Lilium brownie var. viridulum], exhibiting weak inhibition of NO production in LPS-stimulated [RAW 264.7] cells.

1-O-galloyl-6-O-cinnamoylglucose is a natural product for research related to life sciences. The catalog number is TN6483 and the CAS number is 115746-69-5.

1-O-Methylnataloe-emodin is a natural product for research related to life sciences. The catalog number is TN2559 and the CAS number is 103392-51-4.

1-O-p-Coumaroylglycerol is a compound found in Imperata cylindrica and rhizomes of Smilax scobinicaulis and has neuroprotective activity.

1-(Isopropylthio)-2,3,4,6-tetra-O-Ac-beta-D-glucosylpyranose is an alkyl chain-derived PROTAC linker used in the synthesis of PROTACs[1].

Rp-Adenosine-5'-O-(1-thiotriphosphate) (Rp-ATP-α-S), a sulfur-containing nucleotide derivative isomer and a purinergic P2Y1 receptor agonist, promotes calcium mobilization in HEK293 cells expressing the human P2Y1 receptor (EC50 = 75 nM). This compound exhibits binding affinity to washed isolated human platelets (Ki = 156 nM) and attenuates ADP-induced aggregation in human platelet-rich plasma (PRP; pA2 = 4.74), as well as inhibits cAMP production triggered by prostaglandin E1 (PGE1) in human PRP (pA2 = 5.26). Furthermore, it triggers relaxation in carbamoylcholine-constricted guinea pig taenia coli strips (EC50 = 56 nM). Rp-ATP-α-S also contributes to the synthesis of cyclic dinucleotides, recognized by bacterial riboswitches.

Sp-2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), a sulfur-containing isomer of 2'-deoxyguanosine-5'-O-triphosphate (dGTP), functions as an inhibitor of the deoxynucleoside triphosphate triphosphohydrolase SAMHD1, with an inhibitory constant (Ki) of 820 nM.

4-[4-[[6-O-[(2E)-3-(4-Hydroxyphenyl)-1-oxo-2-propen-1-yl]-2-O-(3,4,5-trihydroxybenzoyl)-beta-D-glucopyranosyl]oxy]phenyl]-2-butanone is a natural product for research related to life sciences. The catalog number is TN5281 and the CAS number is 105274-16-6.

2'-O-(2-Propyn-1-yl)adenosine is a Nucleoside Derivative - 2'-Modified nucleoside.

1',2'-Di-O-acetyl-3,5-bis-O-(2,4-dichlorobenzyl)-D-ribofuranoside is a carbohydrate derivative.