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jak in 14

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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JAK-IN-14
T97641973485-06-1
JAK-IN-14 is a potent and selective JAK1 inhibitor with an IC50 of <5 μM, exhibiting over 8-fold selectivity for JAK1 compared to JAK2 and JAK3 [1].
  • $1,570
6-8 weeks
Size
QTY
JAK3-IN-14
T67754454234-24-3In house
JAK3-IN-14 is a potent, selective and orally active FLT3 inhibitor, with IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively.
  • $226
In Stock
Size
QTY
JAK-IN-20
T635811654776-91-6
JAK-IN-20 is a potent, orally active, broad-based JAK inhibitor, effective on JAK1 (IC50: 7 nM), JAK2 (IC50: 5 nM), and JAK3 (IC50: 14 nM), exhibiting excellent pharmacokinetic and anti-inflammatory activity in vivo.
  • $1,520
6-8 weeks
Size
QTY