jak-2 jh2 tracer

JAK2 JH2 Tracer is a fluorescent probe for the JAK2 JH2 domain (Kd: 0.2 μM).

2-NBDG is a fluorescent indicator for direct glucose uptake measurement. It is an indicator of cell viability.

2',7'-Dichlorofluorescein diacetate (Diacetyldichlorofluorescein), a cell-permeable fluorogenic probe, is useful for the detection of nitric oxide (NO) and reactive oxygen species (ROS) and for the determination of the degree of overall oxidative stress.

2-(4-Hydroxyphenylazo)benzoicacid is a spectrophotometric probe that shows changes in absorption spectra upon binding to proteins and binds to bovine serum proteins.

C.I. Vat Yellow 2 (Calcoloid Yellow GCD) is a yellow dye agent that can also be used to detect adsorption behavior on natural sediments.

6-Ethyl-7-hydroxy-4-methylchromen-2-one is a fluorescent dye.

Hoechst 34580 xHCl(23555-00-2(free base) is a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

Rhod-2 AM is a fluorescent probe of the mitochondrion with λex of 552 nm and λem of 581 nm.

Hoechst 33258 analog 2 is part of a family of blue fluorescent dyes used to stain DNA.

2-Aminoacridone is a widely used fluorophore (λexc=428 nm, λem=525 nm).

2-Di-1-ASP is a mono-stryryl dye and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. It has selective for G-quadruplex (G4) and double-stranded DNA.

2-Aminopurine is a double-stranded RNA-dependent protein kinase, protein kinase R (PKR) inhibitor.

SBP-2, a sulfite bioluminescent probe (SBP), detects sulfite through a mechanism involving sulfite-mediated intramolecular cleavage [1].

Mag-Fura-2 AM, a cell-permeable fluorescent compound, serves as a selective indicator for magnesium ions (Mg2+), demonstrating significant preference for Mg2+ over other bivalent ions including zinc (Zn2+), copper (Cu2+), and calcium (Ca2+). It notably exhibits over 13,000-fold greater selectivity for Mg2+ compared to Ca2+ (Mg2+Kd = 1.9 nM vs. Ca2+Kd = 25 μM). The excitation and emission peak wavelengths are 369 nm and 511 nm, respectively. Further, Mag-Fura-2 AM is utilized as an indirect measure of ATP consumption or production due to its magnesium ion sensitivity.

ING-2 AM is a membrane-permeable fluorescent indicator specifically designed for sodium ions (Na+), exhibiting a binding affinity with a dissociation constant (Kd) of 20 mM. With excitation and emission maxima (λ) at 525 nm and 545 nm respectively, this compound achieves a 20-fold selectivity over potassium ions (K+). It is utilized both in vitro and in situ to monitor real-time sodium influx.

2'-Deoxy-1,N6-ethenoadenosine-5'-O-triphosphate (ε-dATP), a fluorescent derivative of 2’-deoxyadenosine-5’-O-triphosphate (dATP), promotes sister chromatid exchange in stimulated primary mouse spleen T- and B lymphocytes with LPS or concanavalin A at concentrations of 50 to 150 µM. Utilized in ambiguous base pairing investigations within vinyl chloride-induced mutagenesis research, ε-dATP, along with its related compound ε-ATP—which exhibits an emission peak at 415 nm after being excited at 300 nm—contributes to understanding genetic alterations mechanisms.

Flutax-2 (5/6-mixture), an active fluorescent derivative of paclitaxel, binds to polymerized α,β tubulin dimers, with an excitation/emission wavelength of 496/524 nm. Derived from paclitaxel, a diterpenoid secondary metabolite from Taxus species utilized in various cancer research [1], it requires storage protection from light.

Sodium 4-(3-(4-hydroxy-5-isopropyl-2-methylphenyl)-1,1-dioxido-3H-benzo[c][1,2]oxathiol-3-yl)-2-isopropyl-5-methylphenolate is a useful organic compound for research related to life sciences. The catalog number is T66669 and the CAS number is 62625-21-2.

CI Direct Brown 2 is a direct dye. It is soluble in water and ionizable to form colored anions. It also can directly dye cellulose fibers or protein fibers.

GNF-2-PEG-acid is usually used as a fluorescent probe.

2-([1,1-Biphenyl]-4-yl)-5-phenyl-1,3,4-oxadiazole is a useful organic compound for research related to life sciences. The catalog number is T66233 and the CAS number is 852-38-0.

C.I. Solvent Orange 2 is an agent of dye.

7-Hydroxy-4-methyl-2(1H)-quinolone (compound 2b), a fluorescent hydroxylated derivative, serves as a probe for detecting hydroxyl radicals associated with DNA damage [1]. It should be protected from light for preservation.

2-Aminobenzamide, a neutral and stable compound, is widely used as a fluorescent tag in glycan analysis and serves as the starting material for several important reactions.

8-(2-azidobenzylthio) NAD+ is a derivatized version of NAD+, a signaling molecule and enzyme cofactor, featuring an azido group (azidobenzylthio) that enables click chemistry applications.

Hoechst 33342 analog 2 is an analog of Hoechst 33342 which is a DNA minor groove binder.

AMCA-X, N-succinimidyl ester is an amine-reactive, UV-excitable, blue fluroscent dye.

tert-Butyl 2-((diphenylmethylene)amino)acetate is a useful organic compound for research related to life sciences. The catalog number is T64928 and the CAS number is 81477-94-3.

2,5-Dioxopyrrolidin-1-yl 2-(7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate is a useful organic compound for research related to life sciences. The catalog number is T67683 and the CAS number is 96735-88-5.

Fura-2 is a ratiometric fluorescent calcium indicator that can be used to detect calcium in cells. It is a pentacarboxylate that displays excitation maxima of 340 and 380 nm at high and low calcium concentrations, respectively, when the emission is fixed at 510 nm, enabling determination of ratiometric measurements of calcium influx in live cells.

Sodium 2,2',2'',2'''-((((1,1-dioxido-3H-benzo[c][1,2]oxathiole-3,3-diyl)bis(6-hydroxy-5-isopropyl-2-methyl-3,1-phenylene))bis(methylene))bis(azanetriyl))tetraacetate is a useful organic compound for research related to life sciences. The catalog number is T65315 and the CAS number is 1945-77-3.

7-(Diethylamino)-4-methyl-2H-chromen-2-one is a useful organic compound for research related to life sciences. The catalog number is T66262 and the CAS number is 91-44-1.

Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 is a potent ruthenium-based dye that serves as an effective quencher for quantum dots (QDs) fluorescence, a capture probe for the virus antigen EV71, and a sensitive label for electrogenerated chemiluminescence (ECL) detection of matrix metalloproteinases (MMPs) [1] [2] [3].

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine, with a phosphatidylethanolamine head group, functions as a fluorescent probe to evaluate surface lipid oxidation in lipoproteins and plasma [1].

NIR-βgal-2, a highly sensitive β-galactosidase-activated near-infrared fluorescent probe, facilitates the visualization of β-galactosidase in breast cancer [1].

N-(2-hydroxyethyl)-Naphthalimide is a fluorescent probe for nucleic acid detection whose fluorescence can be burst.

C.I. Direct Blue 2 is an agent of dye.

Vat Blue 2, a indigo derivative, is a dark blue 5,5'-dibromo-4,4'-dichloroindigo dye.

2-(7-Hydroxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T65277 and the CAS number is 6950-82-9.

2-(7-Methoxy-2-oxo-2H-chromen-4-yl)acetic acid is a useful organic compound for research related to life sciences. The catalog number is T64951 and the CAS number is 62935-72-2.