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jervine hydrochloride

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Jervine HCl
Jervine hydrochloride
T3363L60326-37-6
Jervine is a naturally occurring steroidal alkaloid derived from the Veratrum plant species. Over the Hedgehog signaling pathway, Jervine effectively inhibits tumor growth using three human tumor xenograft models. Jervine has the potential to advance to t
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Jervine
Iervin,11-Ketocyclopamine,Jerwiny
T3363469-59-0
The biological activity of Jervine (Jerwiny) is mediated via its interaction with the 7 passes transmembrane protein Smoothened. Jervine binds with and inhibits smoothened, which is an integral part of the Hedgehog signaling pathways. With smoothened inhibited, the GLI1 transcription cannot be activated and Hedgehog target genes cannot be transcribed.
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Diacetyljervine
NSC-406352,NSC 406352,N-acetyl-,N,O-Diacetyljervine,Jervine,NSC406352
T314157622-06-2
Diacetyljervine is a bioactive chemical.
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