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By Target- Neurokinin receptor
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Results for "
l-785298
" in TargetMol Product Catalog- Inhibitors & Agonists1
Fosaprepitant dimeglumine
L785298,MK-0517,Fosaprepitant dimeglumine salt
T1790265121-04-8
Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, a water-soluble, N-phosphorylated prodrug of aprepitant with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent selectively binds to human substance P neurokinin 1 (NK1) receptors in the central nervous system (CNS), inhibiting receptor binding of endogenous substance P and preventing substance P-induced emesis.
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