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(2)
By Target- ALK
- IGF-1R(2)
- Serine Protease(1)
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Results for "
ldk378
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Isotope Products1
Ceritinib
Cited
LDK378
T17911032900-25-6
Ceritinib (LDK378) is an ALK tyrosine kinase inhibitor (IC50=200 pM) with selective, ATP-competitive, and oral activity. Ceritinib also inhibits IGF-1R, InsR, and STK22D (IC50=8 7 23 nM). Ceritinib has antitumor activity.
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CitedCeritinib dihydrochloride
LDK378 dihydrochloride
T1791L1380575-43-8
Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable, ATP-competitive inhibitor of ALK tyrosine kinase (IC50 of 200 pM) and also inhibits IGF-1R, InsR, and STK22D [IC50 values of 8, 7, and 23 nM, respectively], demonstrating significant antitumor potency.
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Ceritinib D7
LDK378 D7
T107661632484-77-5
Ceritinib D7 (LDK378 D7) is a deuterium-labeled Ceritinib. Ceritinib is an ATP-competitive inhibitor of ALK tyrosine kinase.
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