longifolia

Methyl 4-hydroxycinnamate is an esterified derivative of p-coumaric acid isolated from the flowers of Trixis michuacana var. longifolia, exhibiting antibacterial and anti-melanogenesis properties.

14,15 β-Dihydroxyklaineanone（14,15beta-Dihydroxyklaineanone） is a bittersweet compound isolated from Eurycoma longifolia with antitumor-promoting, antischistosomal and plasmodium-killing activities.

Eurycomalactone is a natural product isolated from Eurycoma longifolia Jack., acts as a potent NF-κB inhibitor( IC50 of 0.5 μM). Eurycomalactone inhibits protein synthesis, depletes cyclin D1, but does not affect TNFα-induced degradation of IκBα or the phosphorylation of IKKα β and IκBα.

7-Methoxy-β-carboline-1-propionic acid (compound 46), recognized for its cytotoxic and antimalarial properties, is derived from the roots of Eurycoma longifolia [1].

Pasakbumin B (13-alpha-(21)-Epoxyeurycomanone) is a bioactive compound from Eurycoma longifolia Jack.

9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilization.9-Hydroxycanthin-6-one inhibits Wnt signaling through the activation of GSK3β independent of CK1α.

1-Methoxymethyl-β-carboline, a natural product, has been isolated from the root of Eurycoma longifolia [1].

13,21-Dihydroeurycomanone (Pasakbumin C) is a natural product isolated from the root of Eurycoma longifolia with antiparasitic activity such as Plasmodium falciparum and Toxoplasma gondii.