lox-in-3 dihydrochloride

LOX-IN-3 dihydrochloride is an inhibitor of lysyl oxidase (LOX). LOX-IN-3 dihydrochloride inhibited bovine LOX (IC50<10 μM) and human LOXL2 (IC50<1 μM)activities.

LOX-IN-3 dihydrochloride monohydrate (Compound 33) is a lysyl oxidase (LOX) inhibitor with oral activity. It is specifically designed for research purposes in the areas of fibrosis, cancer, and angiogenesis [1].

3-Hydroxykynurenamine HCl (3-OH-Kynurenamine HCl) is an immunomodulatory biogenic amine, an intermediate in the catabolism of amino acids, which induces oxidative damage and promotes cell death.

Aniline, 4,4'-pentamethylenedioxybis(3-chloro-, dihydrochloride is a bioactive chemical.

DNA Crosslinker 3 (dihydrochloride) (Compound 1) is a potent minor groove binder, exhibiting a DNA binding affinity (ΔTm) of 1.4°C, and serves as a valuable tool in anticancer research [1].

CARM1-IN-3 dihydrochloride (compound 17b) CARM1-IN-3 dihydrochloride (compound 17b) is a potent, selective coactivator-associated arginine methyltransferase (CARM1) inhibitor that acts on CARM1 (IC50: 0.07 μM) and CARM3 ( IC50>25 μM).

(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65526 and the CAS number is 1354486-07-9.

(S)-2-Amino-3-(pyridin-4-yl)propanoic acid dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66893 and the CAS number is 178933-04-5.

2-(2-(4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethoxy)ethanol dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67203 and the CAS number is 1535-17-7.

N tau-methylhistamine is one of the histamine metabolites. N tau-methylhistamine in plasma and urine is a good parameter for histamine release, and the determination of this histamine metabolite is generally less hampered by possible artifacts (due to bas

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66079 and the CAS number is 1062580-52-2.

COX-2/5-LOX-IN-3 (compound 5b) is a powerful and dual inhibitor of COX-2 and 5-LOX, with IC50 values of 45.73 μM, 5.45 μM, and 4.33 μM for COX-1, COX-2, and 5-LOX, respectively. This compound, COX-2/5-LOX-IN-3, shows promise for the investigation of inflammatory diseases [1].

LOX-IN-3, an orally active inhibitor of lysyl oxidase (LOX), holds potential application in the fields of fibrosis, cancer, and angiogenesis research[1].

COX-2/15-LOX-IN-3 (compound 5k) serves as a dual inhibitor for COX-2 and 15-LOX, demonstrating inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM, respectively. This compound effectively suppresses LPS-induced cellular production of pro-inflammatory cytokines (IL-6, ROS, and NO), exhibiting targeted anti-inflammatory effects [1].

1-Benzyl-4-methyl-3-(methylamino)piperidine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66156 and the CAS number is 1228879-37-5.

(R)-2-Amino-3-(pyridin-4-yl)propanoic acid is a useful organic compound for research related to life sciences. The catalog number is T67056 and the CAS number is 37535-50-5.