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ly 450139

" in TargetMol Product Catalog

Inhibitors & Agonists
1

Semagacestat

T6125425386-60-3

Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42 Aβ40 Aβ38 (IC50: 10.9 12.1 12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).

Beta Amyloid Gamma-secretase

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