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By Target- Gamma-secretase
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Results for "
ly-3039478
" in TargetMol Product Catalog- Inhibitors & Agonists2
LY-3039478 monohydrate
T330111421439-98-6
LY-3039478 monohydrate is a bioactive chemical.
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Crenigacestat
Cited
LY3039478
T36331421438-81-4
Crenigacestat (LY3039478) is an orally bioavailable Notch inhibitor with an IC50 of ~1 nM in most tumor cell lines tested. It effectively inhibits mutant Notch receptor activity and, in a xenograft tumor model, inhibits the expression of Notch-regulated genes and N1ICD cleavage in the tumor microenvironment.
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