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m‑89 (menin-mll inhibitor)

" in TargetMol Product Catalog
  • Inhibitor Products
    10
    TargetMol | Activity
Menin-MLL inhibitor MI-2
T26491271738-62-5
Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
  • $35
In Stock
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QTY
TargetMol | Citations Cited
M‑89
T119252363165-42-6
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia.
  • $169
In Stock
Size
QTY
M‑89 MLL inhibitor
T696292446155-01-5
M‑89 is a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein−Protein Interaction (Kd = 1.4 nM; IC50 = 25nM). M-89 binds to menin with a Kd value of 1.4 nM and effectively engages cellular menin protein at low nanomolar concentrations. M-89 inhibits cell growth in the MV4;11 and MOLM-13 leukemia cell lines carrying MLL fusion with IC50 values of 25 and 55 nM, respectively, and demonstrates >100-fold selectivity over the HL-60 leukemia cell line lacking MLL fusion.
  • $3,920
10-14 weeks
Size
QTY
Menin-MLL inhibitor 29
T79737
Menin-MLL Inhibitor 29 (Compound C1) is a Menin-MLL protein-protein interaction (PPI) inhibitor that demonstrates high affinity to Menin with a dissociation constant (K D) of 138 nM and impedes Menin's interaction with Menin-binding motif 1 (MBM1), as evidenced by an inhibition constant (IC 50) of 46 nM. Additionally, it exhibits anti-proliferative activity against HepG2 and Hep3B hepatoma cell lines with IC 50 values of 0.31 μM and 0.71 μM, respectively, and has been shown to inhibit tumor growth [1].
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(1s,4s)-Menin-MLL inhibitor-23
T72135
(1s,4s)-Menin-MLL Inhibitor-23, an enantiomer of Menin-MLL Inhibitor-23 (Example 99A), functions as an inhibitor of the menin-MLL interaction [1].
  • $1,820
8-10 weeks
Size
QTY
Menin-MLL inhibitor 4
T120022169916-13-4
Menin-MLL inhibitor 4 has antitumor activity.Menin-MLL inhibitor 4 is an inhibitor of Menin- MLL (mixed-lineage leukemia protein) interaction .
  • $2,570
10-14 weeks
Size
QTY
Menin-MLL inhibitor 27
T79117
Menin-MLL inhibitor 27 effectively inhibits the interaction between Menin and MLL, serving as a potential tool in cancer research, particularly for acute myeloid leukemia (AML) [1].
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Menin-MLL inhibitor 26
T723602440018-29-9
Menin-MLL inhibitor 26 is a Menin-MLL inhibitor. Menin-MLL inhibitor 26 also is an active reference. Menin-MLL inhibitor 26 can inhibits cell growth. Menin-MLL inhibitor 26 can be used for the research of leukemia .
  • $3,320
10-14 weeks
Size
QTY
Menin-MLL inhibitor 20
T93992448173-47-3
Menin-MLL inhibitor 20 is an irreversible inhibitor of menin-MLL interaction with antitumor activities.
  • $57
In Stock
Size
QTY
Iptacopan hydrochloride hydrate
T696282447007-60-3
Iptacopan hydrochloride hydrate is a highly potent and highly selective factor B inhibitor.
  • $1,820
1-2 weeks
Size
QTY