m peg3 sulfone peg3 boc

m-PEG3-Sulfone-PEG3-Boc is a polyethylene glycol (PEG)-derived proteolysis-targeting chimera (PROTAC) linker used in the synthesis of PROTACs[1].

DSPE-PEG-OH (MW 2000) is a PEG-based PROTAC linker for PROTAC synthesis.

PC Biotin-PEG3-alkyne is an ADC linker, cleavable 3-unit PEG, which can also be used to synthesize antibody drug conjugates (ADCs).

Pomalidomide-PEG3-OH enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology.

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.

AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.

Biotin-PEG3-OH is a PEG-based PROTAC linker used in PROTAC synthesis.

Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a 3-unit PEG linker, used in PROTAC technology.

Biotin-PEG3-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

m-PEG3-SH (M-PEG3-Thiol) is a PEG-based PROTAC linker. m-PEG3-SH can be used in the synthesis of PROTACs.

Propargyl-PEG3-acid is a non-cleavable (3-unit PEG) ADC linker and a PEG-based PROTAC linker, used to synthesize 6-OHDA-PEG3-yne, a compound containing 6-OHDA and Propargyl-PEG3-acid[1].

Azido-PEG3-azide is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

DBCO-S-S-PEG3-biotin is a cleavable reagent for the introduction of a biotin moiety to azide-containing biomolecules using copper-free Click Chemistry. The disulfide bond in this linker can be cleaved with reducing agents such as DTT, BME, and TCEP to remove the biotin label. PEG linkers can also be used in the synthesis of PROTACs.

PEG3-O-CH2COOH (PROTAC Linker 8) is a PEG-based linker utilized in the synthesis of SNIPERs.

Biotin-PEG3-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. This heterobiofunctional biotin PEG derivative contains a carboxylic acid group. The hydrophilic PEG spacer arm imparts water solubility to the biotinylated molecule. [PEG Linkers] may be useful in the development of antibody-drug conjugates and drug delivery methods.

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Biotin-PEG3-SS-azide (Biotin-PEG3-amido-SS-amido-azide) is a cleavable ADC linker containing 3-unit PEG and can be used to synthesize antibody-drug conjugates (ADCs).

(S,R,S)-AHPC-PEG3-NH2 hydrochloride (E3 ligase Ligand-Linker Conjugates 5) is an E3 ligase ligand-linker conjugate that integrates the (S,R,S)-AHPC-based VHL ligand with a 3-unit PEG linker.

Bromo-PEG3-C2-acid, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis[1].

Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

BM-PEG3 (1,11-Bis-maleimidotetraethyleneglycol) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

S-Acetyl-PEG3-azide, a PEG-based linker for PROTACs, joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG-amine (MW 3400) is a polyethylene glycol (PEG) -based linker used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker with a cleavable bond, frequently used in the production of antibody-drug conjugates (ADCs)[1].

NH2-PEG3 hydrochloride is a PEG-based linker for PROTACs, crucial for joining two essential ligands to form PROTAC molecules. This compound facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Hydroxy-PEG3-acrylate is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

Azido-PEG3-C6-Cl is a PEG-based linker for PROTACs, which connects two essential ligands crucial for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis [1].

LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM for cyclin T1 and 662 nM for CDK9. This compound consists of the CDK9 inhibitor, SNS 032, linked to a hydrophobic tag via a glycol linker. Notably, LL-K9-3 does not affect the degradation of other CDKs (CDK1, 2, 4, 5, 6, and 7). Tested in 22RV1 cells, it effectively reduces androgen receptor (AR) and cMyc expression by inducing the selective and synchronous degradation of CDK9 and cyclin T1.

3-Mercaptopropionic acid NHS ester is a useful organic compound for research related to life sciences and the catalog number is T64663.

Ald-Ph-amido-C2-PEG3-NH-Boc is a polyethylene glycol (PEG)-based bifunctional linker used in the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

N-Hydroxypropyl-N’-(azide-PEG3)-Cy3 is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Azido-PEG3-S-PEG3-azide is a polyethylene glycol (PEG)-derived linker engineered for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Bromo-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-Me-CO-CH2-PEG3-NH2 is a synthetic E3 ligase ligand-linker conjugate composed of a VHL ligand and a linker, utilized in PROTAC BRD4 Degrader-5 and PROTAC BRD4 Degrader-5-CO-PEG3-N3.

Bis-PEG3-PFP ester is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amine-PEG-thiol (MW 5000) is a polyethylene glycol (PEG)-based PROTAC linker primarily used for the synthesis of PROTACs[1].

Methyl 3-hydroxypropanoate is a PROTAC linker compound, which belongs to the alkyl ether family. It is commonly employed in the synthesis of PROTACs.

Bromoacetamide-PEG3-propargyl is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Ald-Ph-amido-PEG3-C-COOH is a noncleavable linker used in the development of antibody-drug conjugates (ADCs).

N-Boc-N-bis(PEG3-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a polyethylene glycol-based PROTAC linker used in the synthesis of PROTACs.

PROTAC BET Degrader-3 is a potent degrader of BET proteins based on the PROTAC (PROteolysis TArgeting Chimera) technology.