mal c6 amine tfa

Mal-C6-amine (TFA) is an alkyl chain-based linker used in the synthesis of PROTACs[1].

Pomalidomide-C6-I TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker.

Tri(Mal-PEG2-amide)-amine, a polyethylene glycol (PEG)-derived linker, is commonly used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Mal-C2-cyclohexylcarboxyl-hydrazide TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

c-Ceritinib TFA salt is a coupleable ceritinib analog with a linker which also binds multiple other kinases, including FAK1, RSK1/2, ERK1/2, CAMKK2 and FER.

Thalidomide-O-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].

3,4-Dibromo-Mal-PEG2-amine is a polyethylene glycol (PEG) derivative that functions as a PEG-based PROTAC linker, enabling the synthesis of PROTACs[1].

Mal-C6-α-Amanitin, an ADC (antibody-drug conjugate) linker drug, incorporates the powerful antitumor agent α-Amanitin, an inhibitor of RNA polymerase II, through the Mal-C6 linker, showcasing potent antitumor activity.

Mal-amido-PEG9-amine, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Mal-PEG6)-N-bis(PEG3-amine) is a Polyethylene Glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker used in the synthesis of PROTACs[1].

N-Mal-N-bis(PEG4-amine) is a PEG-based linker used in PROTAC synthesis [1].

Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG2-NH2 TFA is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG4-Lys(TFA)-NH-m-PEG24 is a polyethylene glycol (PEG) derivative designed as a PROTAC linker for synthesizing proteolysis targeting chimeras (PROTACs) [1].

Thalidomide-NH-C6-NH2 TFA is a synthetic conjugate compound that integrates a cereblon ligand derived from Thalidomide with a linker used in PROTAC technology, serving as an E3 ligase ligand-linker conjugate[1].

Mal-PEG4-C2-NH2 TFA, a PEG-based linker, facilitates the assembly of PROTAC molecules by connecting two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-Mal-N-bis(PEG2-amine) is a polyethylene glycol (PEG)-based linker compound commonly used in the construction of PROTACs, or proteolysis-targeting chimeras[1].

Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) linker essential for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-Gly-amido-C-PEG3-C3-amine is a polyethylene glycol (PEG)-based PROTAC linker used in PROTAC synthesis [1].