mal peg2 acid

Mal-PEG2-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It can be conjugated to Tubulysin and its derivative cytotoxic molecule [1].

N-Mal-N-bis(PEG2-acid) is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system in cells.

Mal-amido-PEG2-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands to form PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Mal-amido-PEG7-acid (Mal-NH-PEG7-COOH) is a PEG-based PROTAC linker that can be used to synthesize PROTACs.

2-Phthalimidehydroxy-acetic acid is an alkyl chain-based PROTAC linker utilized in PROTAC synthesis.

Mal-PEG2-C2-Boc (Mal-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. Mal-PEG2-C2-Boc can be used in the synthesis of PROTACs.

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and FGF21-receptor agonist, suitable for development as a potential treatment for T2DM.

Cl-PEG2-acid is a PEG-based linker for PROTACs, essential for joining two ligands critical to forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-C2-SS-PEG2-C2-acid is a cleavable PEG linker with two units used in the synthesis of antibody-drug conjugates (ADCs) [1].

2-(Azido-PEG2-amido)-13-propandiol is a Polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs[1].

Mal-PEG2-alcohol, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG-mal (MW 3400) is a PEG-based linker for PROTACs that joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system in cells.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

N-Mal-N-bis(PEG2-amine) is a polyethylene glycol (PEG)-based linker compound commonly used in the construction of PROTACs, or proteolysis-targeting chimeras[1].

The compound 3,4-Dibromo-Mal-PEG8-acid is a PEG-based PROTAC linker employed for PROTAC synthesis[1].

Mal-PEG2-VCP-Eribulin is a chemotherapeutic compound comprising an antibody-drug conjugate (ADC) linker (Mal-PEG2-VCP) and the microtubule inhibitor Eribulin[1]. This compound uniquely targets microtubules, offering a novel approach to cancer treatment. Eribulin is specifically utilized in creating targeted Eribulin-based drugs for antibody conjugates[1].

Mal-PEG2-NH2 is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG2-C2-sulfonic acid, a PEG-based linker for PROTACs, connects two essential ligands critical for forming PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-DBCO-N-bis(PEG2-C2-acid) is a polyethylene glycol (PEG) linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bromo-PEG2-phosphonic acid diethyl ester is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs) [1].

Boc-PEG2-sulfonic acid is a PEG-based linker for PROTACs, joining two essential ligands and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

m-PEG2-phosphonic acid is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-PEG2-acid is a PEG-based linker used in PROTACs, connecting two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

PEG2-bis(phosphonic acid diethyl ester) is a polyethylene glycol (PEG) derivative frequently used as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative used as a PEG-based PROTAC linker for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG2-PFP ester, an alkyl ether-based PROTAC linker, facilitates the synthesis of PROTACs.

Bis-CH2-PEG2-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG2-mal, a PEG-based linker for PROTACs, joins two essential ligands, crucial for forming PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a polyethylene glycol (PEG)-derived PROTAC linker designed for PROTAC synthesis[1].

Mal-amido-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG2-Mal is a PEG-based linker for PROTACs that joins two essential ligands necessary for forming PROTAC molecules, facilitating selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Amino-PEG2-C2-acid, a cleavable 3-unit PEG ADC linker, is used in the synthesis of antibody-drug conjugates (ADCs) [1].

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker used in the development of proteolysis targeting chimeras (PROTACs)[1].

endo-BCN-PEG2-acid, a PEG-based linker for PROTACs, connects two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Mal-NH-PEG2-CH2CH2COOPFP ester, a polyethylene glycol (PEG) derived linker, is specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-PEG1-acid is a non-cleavable (1 unit PEG) ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

m-PEG2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

HO-PEG-mal (MW 3400) is a PEG-based linker for PROTACs, joining two essential ligands necessary for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-amido-PEG12-acid is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by connecting two essential ligands and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Bis-Mal-Lysine-PEG4-acid is a PEG-based PROTAC linker used for PROTAC synthesis [1].

3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-derived PROTAC linker used for synthesizing PROTACs [1].

Mal-PEG-Succinimidyl Valerate (MW 20000) is a polyethylene glycol (PEG)-based linker with a molecular weight of 20000, crucial for synthesizing proteolysis targeting chimeras (PROTACs).

m-PEG-mal (MW 5000) is a PEG-based linker used in PROTACs to connect two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Propargyl-PEG2-acid is a non-cleavable 2-unit PEG ADC linker used in synthesizing antibody-drug conjugates (ADCs)[1].

3,4-Dibromo-Mal-PEG2-amine is a polyethylene glycol (PEG) derivative that functions as a PEG-based PROTAC linker, enabling the synthesis of PROTACs[1].

(2-Pyridyldithio)-PEG4 acid is a four-unit cleavable polyethylene glycol (PEG) linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. It serves as a crucial component in the conjugation of antibodies and drugs, enabling targeted drug delivery and enhanced therapeutic efficacy. This linker possesses a (2-pyridyldithio) group at one end, facilitating the attachment of the linker to the specific site on the antibody molecule. The PEG4 chain provides the necessary flexibility and biocompatibility for optimal drug release while maintaining stability throughout the circulation in the body. Ultimately, (2-Pyridyldithio)-PEG4 acid is instrumental in the development and advancement of ADCs, a promising approach in cancer therapy.

Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker used for synthesizing PROTACs[1].