mal-nh2 tfa

Mal-NH2 TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG2-NH2 TFA is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG4-C2-NH2 TFA, a PEG-based linker, facilitates the assembly of PROTAC molecules by connecting two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Thalidomide-NH-C6-NH2 TFA is a synthetic conjugate compound that integrates a cereblon ligand derived from Thalidomide with a linker used in PROTAC technology, serving as an E3 ligase ligand-linker conjugate[1].

Thalidomide-NH-CBP p300 ligand 2 (P-007) is a PROTAC-based compound engineered to degrade the proteins CBP and p300, functioning as a molecular antagonist (WO2020173440).

Mal-PEG4-Lys(TFA)-NH-m-PEG24 is a polyethylene glycol (PEG) derivative designed as a PROTAC linker for synthesizing proteolysis targeting chimeras (PROTACs) [1].

Mal-L-PA-NH-Boc, a noncleavable ADC linker, facilitates the synthesis of antibody-drug conjugates (ADCs).

Mal-NH-ethyl-SS-propionic acid, a cleavable linker employed for the synthesis of antibody-drug conjugates (ADCs)[1], plays a crucial role in the modulation of drug release from the conjugate.

Mal-C2-cyclohexylcarboxyl-hydrazide TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-NH-PEG14-CH2CH2COOPFP ester is a polyethylene glycol-based (PEG) linker used in PROteolysis TArgeting Chimeras (PROTACs) [1].

Mal-amido-PEG9-NH-Boc is a PEG-based linker for PROTACs that connects two vital ligands, essential for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-NH-C4-NH2 TFA (compound 29c) is a conjugate composed of an E3 ligase ligand-linker that integrates a Thalidomide-based cereblon ligand and a linker moiety. This compound is used as a component in PROTAC BRD2 BRD4 degrader-1, a highly potent and selective degrader targeting BET proteins BRD4 and BRD2[1].

Mal-NH-PEG12-CH2CH2COOPFP ester is a polyethylene glycol (PEG) based linker molecule designed specifically for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Mal-NH-PEG16-CH2CH2COOPFP ester is a polyethylene glycol-based linker designed for synthesizing proteolysis targeting chimeras (PROTACs) [1].

Mal-NH-PEG10-CH2CH2COOPFP ester is a polyethylene glycol (PEG)-based linker molecule used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Mal-NH-Boc is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-C6-amine (TFA) is an alkyl chain-based linker used in the synthesis of PROTACs[1].

Mal-C4-NH-Boc is a alkyl ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-NH-PEG2-CH2CH2COOPFP ester, a polyethylene glycol (PEG) derived linker, is specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Mal-NH-PEG8-CH2CH2COOPFP ester is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Mal-PEG4-Glu(TFP ester)-NH-m-PEG24 is a polyethylene glycol (PEG)-based linker crucial for synthesizing proteolysis targeting chimeras (PROTACs)[1].

PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2) degrader with potential applications in cancer and metabolic disease research [1].

Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker used in the synthesis of PROTACs [1].

Mal-amido-(CH2COOH)2, also known as compound 7a, is an intermediate compound that contains maleimidoethyl for use in hydrophilic ADC linker synthesis[1].

Mal-NH-PEG24-CH2CH2COOPFP is a polyethylene glycol (PEG)-based ester, serving as a PROTAC linker in the synthesis of PROTACs[1].

Mal-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands fundamental for forming PROTAC molecules and facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Mal-PEG4-Lys(t-Boc)-NH-m-PEG24 is a polyethylene glycol (PEG)-based PROTAC linker, ideal for PROTAC synthesis[1].

Mal-NH-PEG6-CH2CH2COOPFP ester, a polyethylene glycol (PEG)-based linker, is specifically designed for the synthesis of PROTACs and is known as a PROTAC linker[1].

Mal-PEG4-Glu(OH)-NH-m-PEG24 is a polyethylene glycol-based (PEG-based) linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Mal-NH-PEG4-CH2CH2COOPFP ester, a polyethylene glycol (PEG) based linker, is used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.