mc(c5)valcit

5-ETHYL-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4-C]PYRIDIN-2-YLAMINE targets PLK1.

7-Methoxy-8-(3-morpholin-4-ylpropoxy)-2,3-dihydroimidazo[1,2-c]quinazolin-5-amine is a building block.1It has been used in the synthesis of PI3K inhibitors. 1.Scott, W.J., Hentemann, M.F., Rowley, R.B., et al.Discovery and SAR of novel 2,3-dihydroimidazo[1,2-c]quinazoline PI3K inhibitors: Identification of copanlisib (BAY 80-6946)ChemMedChem.11(14)1517-1530(2016)

5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog belonging to the class of modified antisense oligonucleotide [1].

3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).

MC(C5)-Val-Cit is a cleavable ADC linker employed in ADCs synthesis [1].

5'-O-Benzoyl-2'-O,4'-C-methyleneuridine is a Nucleoside Derivative - LNA related nucleoside; Protected nucleoside with NH2/OH open.

5'-O-Benzoyl-3'-O-(4-methoxybenzoyl)-2'-O,4'-C-methyleneuridine is a Nucleoside Derivative - LNA-related nucleoside.

Nucleoside Derivatives - 5’-Modified nucleosides; 6-Modified purine nucleosides; N-Methylated nucleosides

5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66095 and the CAS number is 720720-96-7.

5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties. Its analogues are instrumental in investigating anticonvulsant and anxiolytic effects and are pivotal in crafting novel antihypertensive agents [1].

1-(2-C-b-Methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a Pyridine nucleoside; 2'-C-Methyl nucleoside.

Nucleosides and Reagents - Fluoro-modified nucleoside; 2’-C-methyl nucleoside; ; 5-Modified pyrimidine nucleoside

Nucleoside Derivatives - 2’-Modified nucleosides, 5-Modified pyrimidine nucleosides

5'(R)-C-Methylguanosine is a Nucleoside Derivative - 5'-Modified nucleoside.

2'-C-Methyl-5-methyluridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

Rev 2’-O-MOE-C(Bz)-5’-amidite; N4-Benzoyl-3'-O-(4,4’-dimethoxy trityl)-2'-O-(2-methoxyethyl)cytidine-5’-CED phosphoramidite is a useful organic compound for research related to life sciences and the catalog number is TNU1531.

Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene][[5-[(dimethylamino)sulfonyl]-2-(1-methylethoxy-O)phenyl]methylene-C]ruthenium(II) is a useful organic compound for research related to life sciences and the catalog number is T66135.

Nucleoside Derivatives - 5’-Modified nucleosides, 5-Modified pyrimidine nucleosides

5'(R)-C-Methyluridine is a Nucleoside Derivative - 5'-Modified nucleoside.

2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-methyluridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-fluoromethyl-D-ribofuranose is a Carbohydrate Derivative.

N-Trityl-N4-benzoyl-morpholino-C-5'-O-phosphoramidite is a Nucleoside Derivative - Morpholino nucleoside; Phosphoramidite.

5-O-Benzoyl-1,2,3-tri-O-acetyl-4-C-methyl-D-ribofuranose is a Carbohydrate Derivative.

2'-C-Methyl-5-methoxyuridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

tert-Butyl 4,6-dihydropyrrolo[3,4-c]pyrazole-5(2H)-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66374 and the CAS number is 1280210-79-8.

5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent lymphoid malignancies. Its anticancer mechanisms include inhibiting DNA synthesis and inducing apoptosis, among others [1].

'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and induction of apoptosis, among others [1].'

5-Chloro-3-phenylbenzo[c]isoxazole is a useful organic compound for research related to life sciences. The catalog number is T66589 and the CAS number is 719-64-2.

5-Iodo-2'-C-methyl uridine is a 2'-C-Methyl nucleoside; Halo-nucleoside.

5-O-Benzoyl-4-C-hydroxymethyl-2,3-O-isopropylidene-1-O-methyl-beta-D-ribofuranose is a Carbohydrate Derivative.

2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-methoxyuridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

3'-beta-C-Methyl-5-methyluridine is a Nucleoside Derivative - 3'-Modified nucleoside.

4'-C-Methyl-5-methylcytidine is a Nucleoside Derivative - 4'-Modified nucleoside.

Nucleoside Derivatives - 5’-Modified nucleosides; 3-Deazauridines

5-Fluoro-4'-C-methyluridine is a Nucleoside Derivative - 4'-Modified nucleoside; Fluoro-modified nucleoside; 5-Modified pyrimidine nucleoside.

2'-beta-C-Ethynyl-5-methyluridine is a Nucleoside Derivative - 2'-Modified nucleoside.

5-Methyl-2'-O,4'-C-methylenecytidine is a Nucleoside Derivative - LNA-related nucleoside.

Nucleoside Derivative –4’-Modified nucleosides; Protected nucleosides with NH2/OH group

Scaffolds and Templates; Heterocyclic Compounds - Fused polyheterocycles

Nortrachelogenin-5'-C-beta-glucoside is a natural product of Trachelospermum, Apocynaceae. The catalog number is TN6509 and the CAS number is 858127-39-6. Nortrachelogenin-5'-C-beta-glucoside can be used as a reference standard.

5-Fluoro-3'-beta-C-methyluridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.

1-(2,3,5-Tribenzoyl-2-C-b-methyl-b-D-ribofuranosyl)-5-nitropyridine-2(1H)-one is a Pyridine nucleoside; 2'-C-Methyl nucleoside.

3'-Deoxy-3'-a-C-methyl-5-fluorouridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside, Fluoro-modified nucleoside.

Nucleoside Derivatives - 2’-Modified nucleosides; Scaffolds and Templates;Bi-Tricyclic nucleosides

Cathepsin C-IN-5 (compound SF38) is a potent, selective, and orally active inhibitor of Cathepsin C, demonstrating IC50 values of 59.9 nM for Cat C, and showing significantly lower potency against Cat L (4.26 µM), Cat S, Cat B, and Cat K (all >5 µM). It effectively reduces Cat C activity in bone marrow and blood, diminishes the activation of NSPs (neutrophil serine proteases), and exhibits anti-inflammatory activity [1].

2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-fluorouriddine is a Fluoro-modified nucleoside; 2'-C-methyl nucleoside; 5-Modified pyrimidine nucleoside.

Nucleoside Derivatives - 3’-Modified purine nucleosides

3'-beta-C-Methyl-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.

c-Myc Inhibitor 5 (DA3) is a fluorescent bispurine compound with a long-chain bridge that selectively binds to the c-MYC G-quadruplex, exhibiting a dissociation constant (K D) of 16 μM. Unlike other G4-driven oncogenes, this inhibitor specifically suppresses c-MYC expression [1].

CL845-PAB-Ala-Val-C5-MC, a conjugatable STING ligand, derives from the proprietary cyclic dinucleotide CL845 and is designed for bioconjugation.