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medi4736

" in TargetMol Product Catalog

Inhibitors & Agonists
1
Inhibitory Antibodies
1

Durvalumab

T111261428935-60-7

Durvalumab (MEDI 4736) is a humanized monoclonal antibody targeting PD-L1. It can block the interaction of PD-L1 with PD-1 and CD80, with IC50 values of 0.1 and 0.04 nM, respectively. Durvalumab is often used in combination with platinum-based compounds for the treatment of non-small cell lung cancer and advanced hepatocellular carcinoma cells.

PD-1/PD-L1

$228

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