methyl 5 methylnicotinate

Methyl 5-methylnicotinate is used as pharmaceutical intermediates.

5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.

Methyl 5-hydroxy-1H-indole-3-carboxylate (5-hydroxy-1H-indole-3-carboxylic acid methyl ester) is a marine derived natural products found in Hyrtios erectus.

((3S,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate is a pharmaceutical intermediate used in the synthesis of posaconazole with anticancer activity.

4-(2-chloro-4-methoxy-5-methylphenyl)-N-[(1A)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]-5-methyl-N-(2-propyn-1-yl)-2-thiazolamine is an enantiomeric counterpart of SSR-125543. SSR-125543 is a potent CRF-R1 antagonist with Ki = 1.0 nM for human CRF-R1.

Methyl 3-[2-[[(4R)-4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl]methylamino]ethyl]benzoate is a biochemical reagent that can be used to synthesize active compounds.

5-Bromo-1H-Indole-3-Carboxylic Acid Methyl Ester (Methyl 5-bromo-1H-indole-3-carboxylate) is a marine derived natural products found in Smenospongia sp.

ETHYL 2-AMINO-4-METHYL-5-PHENYLTHIOPHENE-3-CARBOXYLATE targets the prostaglandin E2 receptor EP2 subtype (human)

1H-Pyrazole-5-carboxamide, 4-(5-chloro-2-furanyl)-1,3-bis(2,4-difluorophenyl)-4,5-dihydro-5-methyl-N-[(4-methyl-2-morpholinyl)methyl] is an antifibrotic agent.

Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.

MitoBloCK-6 is an effective inhibitor of Erv1/ALR with IC50 values of 900 nM and 700 nM, respectively. Additionally, MitoBloCK-6 inhibits Erv2 (IC50=1.4 μM). It induces apoptosis in hESCs by promoting the release of cytochrome c.

2-amino-4-methyl-1,3-thiazole-5-carbohydrazide (AMTCH) has antitumor activity and inhibits the growth of cancer cells by inducing apoptosis or programmed cell death. It also has antibacterial and fungal activity.

4-[(2,4-dioxo-1,3-thiazolidin-5-ylidene)methyl]benzoic acid is a synthetic compound with potent antitumor activity, high efficiency and selectivity against tumor cells. However, it has poor solubility in water and is potentially toxic at high concentrations.

2'-O-Methyl-5-iodouridine (5-Iodo-2'-O-methyluridine) is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of antitumor activity. The anticancer mechanism of 2'-O-Methyl-5-iodouridine is dependent on the inhibition of DNA synthesis and induction of apoptosis.

Benzonitrile, 4-[[5-cyclopropyl-3-methyl-1-[(methylsulfonyl)methyl]-1H-pyrazol-4-yl]oxy]-2,6-dimethyl- is a progesterone receptor antagonist with antiprogestin effects.

4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid is used as a pharmaceutical intermediate.

4-Hydroxy-5-methyl-3-furanone (4-Hydroxy-5-methylfuran-3(2H)-one) is a natural product isolated from Eurycotis floridana.

Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

methyl 5-(3,4-dimethoxyphenyl)isoxazole-3-carboxylate is a biochemical.

ethyl 1-[(4-cyanobenzyl)oxy]-2-(3-cyanophenyl)-4-methyl-1H-imidazole-5-carboxylate is a platelet aggregation inhibitor.

1-[(5-methylisoxazol-3-yl)methyl]piperazine (Piperazine, 1-[(5-methyl-3-isoxazolyl)methyl]-) is a P2Y12 inhibitor.

Compound 5936-0108 may has modulationg effect on β-Amyloid.

3',5-Di-O-methyl quercetin (3,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-5-methoxy-4H-chromen-4-one) is a flavonoid natural product.

5-(5-methyl-1H-1,2,4-triazol-3-yl)-3-[4-(trifluoromethoxy)phenyl]-1,2,4-oxadiazole can be used in the synthesis of heterocyclic compounds to inhibit HIF pathway activity.

methyl 5-bromo-1H-pyrrole-2-carboxylate is a marine derived natural products found in Lissodendoryx sp.

rel-5-(4-Chloro-2-fluorophenyl)-2,3-dimethyl-7-[(2R,4S)-tetrahydro-2-(1-methyl-1H-pyrazol-4-yl)-2H-pyran-4-yl]pyrido[3,4-b]pyrazine has an EC50 value of ≤ 0.05 μM and an E.max value of > 250 μM for TREM2.

methyl(Z)-4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-en-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

methyl4-(2-amino-5-(4-((dimethylamino)methyl)thiophen-2-yl)pyridin-3-yl)-2-((5,5,5-trifluoropent-3-yn-2-yl)oxy)benzoate is a useful compound for the synthesis of a variety of organic compounds.

6-Methyl-5-azacytidine is a potent DNMT inhibitor.

4-(3-Methyl-5-oxo-2-pyrazolin-1-yl)benzoic acid exhibits hypoglycemic activity and operates through a mechanism dependent on the response to oral glucose overload.

(±)4(5)-EpDPA methyl ester is a derivative of (±)4(5)-EpDPA which is stable enough to ship and handle routinely. The active free acid can be regenerated from the methyl ester by careful base hydrolysis. (±)4(5)EpDPA is a CYP450 metabolite of DHA which can be further metabolized to the diol metabolite. There are no published reports on the biological activity of (±)4(5)-EpDPA methyl ester at this time.

Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.

N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].

2-Amino-5-methyl-3-thiophenecarbonitrile is commonly used in the synthesis of Olanzapine.

N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription.

5-Hydroxyalizarin 1-methyl ether is a quinone compound that has been isolated from the plant Hymenodictyon excelsum [1].

4,5-Dihydroxy-2-((5-methyl-3,8-dimethylene-2-oxododecahydroazuleno[6,5-b]furan-5-yl)oxy)tetrahydro-2H-pyran-3-yl acetate is an α-arabinopyranosides analogue isolated from the aboveground parts of barley [1].

(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.(±) 5(6)-EpETE methyl ester is a chemically less reactive derivative of 5(6)-EpETE. The active free acid can be generated from the methyl ester by careful base hydrolysis. Epoxy eicosatetraenoic acids (EpETEs) are the epoxygenase metabolites of EPA. A number of vicinal diol metabolites of EpETEs have been detected in the plasma of patients on marine oil dietary supplementation, while in subjects on a typical western diet these compounds are generally not detected. The specific biologic activity of 5(6)-EpETE and its methyl ester have not been documented.

4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a natural product for research related to life sciences. The catalog number is TN2994 and the CAS number is 170380-68-4.

Methyl 2-amino-5-bromobenzoate (Methyl 5-Bromoanthranilate) is a hepatitis C virus NS5b RNA polymerase inhibitor with antimicrobial activity that inhibits Pseudomonas aeruginosa infections and is involved in the production of many virulence factors and biofilm formation.

5-hydroxy-Nω-methyl Tryptamine is a metabolite of serotonin in humans that has also been found in plants. It is an agonist of the 5-HT receptor subtype 5-HT7 (IC50 = 23 pM in a radioligand binding assay). 5-hydroxy-Nω-methyl Tryptamine increases intracellular cyclic AMP production in HEK293 cells expressing 5-HT7 (EC50 = 22 nM). It inhibits serotonin uptake in HEK293 cells expressing human serotonin transporters (IC50 = 490 nM). Elevated levels of urinary 5-hydroxy-Nω-methyl tryptamine have been found in patients with schizophrenia, depression, and epilepsy.

Pinobanksin 5-methyl ether can induce detoxification genes.

Compound 1, (2,4,6-Trichloro-3-hydroxy-5-methoxyphenyl)methyl β-D-glucopyranoside, is a chlorophenyl glycoside extractable from Lilium regale, a species utilized in lung ailment research [1].

N1-[5-[[[3-(4-Amino-2-methylphenyl)-1-methyl-1H-indazol-5-yl]carbonyl]amino]-2-methylphenyl]-N4-methyl-1,4-benzenedicarboxamide is a potent, selective second bromodomain (BD2) of BRDT and BRD4 inhibitor with IC50 of 7 and 25 nM, >1,000-fold and 300-fold selectivity over BRDT-BD1 and BRD4-BD1.

3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).

Benzamide, N-(decahydro-2-methyl-5-isoquinolyl)-3,4,5-trimethoxy-, cis- is a bioactive chemical.

5-(1-Hydroxy)(methoxycarbonyl)methyl uridine is a Nucleoside Derivative - 5-Modified pyrimidine nucleoside; Naturally modified ribo-nucleoside.

Mead acid, a 20-carbon ω-9 polyunsaturated fatty acid, experiences elevated levels in human plasma under conditions of essential fatty acid deficiency. As 1,25(Z),8(Z),11(Z)-Eicosatrienoic Acid methyl ester (Mead acid methyl ester), it frequently serves as a standard for fatty acid analysis, particularly after fatty acids have been transesterified into methyl esters.

Nucleoside, halo-nucleoside, 2’-O-Methyl nucleoside

5’-O-DMTr-5-MedC(Ac)-methyl   phosphonamidite is a useful organic compound for research related to life sciences and the catalog number is TNU1520.