mh 12-43 hydrochloride

UNC0064-12 hydrochloride is an inhibitor of VEGFR2.

EIPA hydrochloride also inhibits Na+/H+-exchanger (NHE) and macropinocytosisEIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM.

GSK2945 hydrochloride is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist (EC50s: 21.5 μM and 20.8 μM). It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.

LP 12 hydrochloride is a selective 5-HT7 receptor agonist (Ki=0.13 nM). LP 12 hydrochloride is selective for 5-HT7 over D2, 5-HT1A, and 5-HT2A receptors (Ki values of 224 nM, 60.9 nM, and >1000 nM, respectively).

LP 12 hydrochloride hydrate is a selective and potent agonist at the 5-HT7 receptor (Ki: 0.13 nM) and is more selective for the 5-HT7 receptor than the D2 receptor (Ki: 224 nM), 5-HT1A receptor (Ki: 60.9 nM), and 5-HT2A receptor (Ki: >1000 nM).

SM-164 Hydrochloride is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains(IC50 value of 1.39 nM) and functions as an extremely potent antagonist of XIAP.

RU-SKI 43 hydrochloride is a potent and selective inhibitor of Hedgehog acyltransferase (Hhat) with an IC50 of 850 nM and exhibits anti-cancer activity.