mogroside iii a1

Mogroside III-A1 is a triterpenoid glycoside derived from Siraitia grosvenorii Swingle, serving as a nonsugar sweetener.

Mogroside III-A2 exhibits inhibitory effects with IC50 values of 346-400 mol ratio 32 pmol TPA. and shows weak inhibitory effects on activation of (+ -)-(E)-methyl-2-[(E)-hydroxyimino]-5-nitro-6-methoxy-3-hexemide (NOR 1), a nitric oxide (NO) donor.

Mogroside III, a triterpenoid glycoside and nonsugar sweetener, is transformed by human intestinal bacteria to release secondary glycoside (mogroside IIA1) and aglycone [mogrol].

Mogroside III-E, a cucurbitane-type compound isolated from Siraitia grosvenorii, exhibits anti-inflammatory activity by attenuating LPS-induced acute lung injury in mice through the regulation of the TLR4 MAPK NF-κB axis via AMPK activation. Additionally, it demonstrates anti-fibrotic activity by reducing pulmonary fibrosis through Toll-Like receptor 4 pathways.

Mogroside I A1, a triterpenoid glycoside isolated from extracts of Luo Han Guo, exhibits antioxidant, antidiabetic, and anticancer activities.

Mogroside IA-(1-3)-glucopyranoside is a natural product isolated from *Siraitia grosvenorii* (Luo Han Guo).