mpegthiol (mw 20000)

Biotin-PEG-Alk (MW 20000) is a biotin-labeled polyethylene glycol (PEG) derivative featuring a terminal alkyne group for efficient click chemistry applications. Serving as an enzymatic cofactor, biotin provides specific labeling of proteins, while the hydrophilic PEG moiety offers solubility and low toxicity. The alkyne functionality enables copper-catalyzed azide-alkyne cycloaddition (CuAAC), enhancing target binding through reaction with azide-modified molecules.

Biotin-PEG-OH (MW 20000) serves as a polyethylene glycol (PEG)-based PROTAC linker suitable for synthesizing PROTACs [1].

Biotin-PEG-Biotin (MW 20000) is a bifunctional PEG derivative featuring biotin labels at each terminal end. As an enzyme co-factor, biotin facilitates protein labeling, while PEG, known for its hydrophilic nature and low toxicity, confers water solubility to the compound.