mti446

Dinotefuran (MTI-446) is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.

(R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, demonstrates insecticidal activities 1.7-2.4 times more effective against typical sucking pests like Aphis gossypii and Apolygus lucorum compared to its racemic mixtures, by targeting nicotinic acetylcholine receptors, and is effective in managing these pests while posing a reduced risk to honeybees [1].

(S)-Dinotefuran ((S)-MTI-446), a neonicotinoid pesticide, exhibits toxicity through interaction with the α8 subunit of the nAChR in the honeybee Apis mellifera (Apis mellifera Linnaeus), demonstrating greater toxicity to Apis mellifera compared to its R-dinotefuran counterpart [1].

Dinotefuran-d3 is a deuterated compound of Dinotefuran. Dinotefuran has a CAS number of 165252-70-0. Dinotefuran is an insecticide of the neonicotinoid class for control of insect pests such as aphids, whiteflies, thrips, leafhoppers, leafminers. Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors.