n-boc-n-bis(peg3-nhs ester)

N-Boc-N-bis(PEG3-NHS ester) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Azido-PEG12-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.

N3-C4-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

DBCO-PEG3-NHS ester is a degradable ADC linker that can be used to synthesize antibody-coupled active molecules.

BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol di-Ph ether scaffold-based programmed cell death-1 (PD-1)/programmed cell death ligand 1 (PD-L1) inhibitor that inhibits the PD-1/PD-L1 interaction with an IC50 of 39.2 nM.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride contains the target protein PD-1/PD-L1 ligand and PROTAC linker.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride can be used to synthesize PROTAC linker. BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride can be used to synthesize PROTAC PD-1/PD-L1 degrader-1. BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride has anticancer activity. BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride can be used as a diluent for the preparation of tablets for direct compression.

Mal-amido-PEG12-NHS ester is a polyethylene glycol (PEG)-derived linker for proteolysis-targeting chimeras (PROTACs)[1]. It is employed in the synthesis of PROTACs, enabling the conjugation of desired target-specific ligands for protein degradation[1].

N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].

N'-Boc-N-(Gly-Oleoyl)-Lys is an alkyl chain-derived proteolysis targeting chimera (PROTAC) linker suitable for PROTAC synthesis [1].

N-(Azido-PEG4)-N-bis(PEG4-acid) is a polyethylene glycol (PEG) derived PROTAC linker, facilitating PROTAC synthesis[1].

Oleoyl-Gly-Lys-N-(m-PEG11) is a cleavable 11 unit PEG linker utilized for the synthesis of antibody-drug conjugates (ADCs)[1].

Hydroxy-Amino-bis(PEG1-C2-Boc) is an alkyl/ether-based linker used for the synthesis of PROTACs[1].

Mal-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG2)-N-bis(PEG4-Boc) is a polyethylene glycol (PEG)-based PROTAC linker, employed for the efficient synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC).

NHPI-PEG3-C2-NHS ester is a three-unit PEG linker compound, noncleavable in nature, specifically employed in the synthesis of antibody-drug conjugates (ADCs).

N-DBCO-N-bis(PEG2-C2-acid) is a polyethylene glycol (PEG) linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Azido-PEG24-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Boc-PEG4-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimeric (PROTAC) linker employed in PROTAC synthesis[1].

Ald-Ph-NHS ester is a non-cleavable linker used in antibody-drug-conjugation (ADC).

Azido-PEG5-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Boc-PEG2)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-derived linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(NHS-PEG3)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-based linker commonly utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Fmoc-N-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

PC Methyltetrazine-PEG4-NHS carbonate ester is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Azido-PEG16-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Endo-BCN-PEG8-NHS ester is a polyethylene glycol (PEG) derivative functionalized with N-hydroxysuccinimide (NHS) ester moiety, utilized as a linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

TCO-PEG12-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

t-Boc-Aminooxy-PEG4-NHS ester is a polyethylene glycol (PEG) derivative, functioning as a linker for PROTAC synthesis[1].

N-(Acid-PEG2)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-based linker. It is utilized in the synthesis of proteolysis targeting chimeras (PROTACs), a unique class of molecules designed for targeted protein degradation[1].

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor acting as a toxin payload in antibody-drug conjugates, is conjugated to a DBCO-(PEG)3-vc-PAB linker.

Bis-PEG6-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-bis(PEG4-acid) is a polyethylene glycol-based linker, designed specifically for the synthesis of PROTACs.[1]

SPDP-PEG36-NHS ester is a PEG ADC linker consisting of 36 units, characterized by cleavability. It plays a crucial role in the synthesis of antibody-drug conjugates (ADCs)[1].

Cy5-PEG6-NHS ester (chloride) is a PEG-based PROTAC linker utilized for PROTACs[1] synthesis.

Bis-PEG9-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Azido-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG25-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

3,4-Dibromo-Mal-PEG2-N-Boc is a PEGylated PROTAC linker utilized in PROTAC synthesis[1].

N-Azido-PEG4-N-Boc-N-PEG3-Boc is a PEG-based linker compound employed for the synthesis of PROTACs. [1]

TCO-PEG8-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG6-NHS ester is a noncleavable ADC linker consisting of a Maleimide functional group, a 6-unit Polyethylene Glycol (PEG) spacer, and an N-Hydroxysuccinimide (NHS) ester moiety.

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2].

(E)-TCO-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Methyltetrazine-PEG5-NHS ester, a PEG-linked PROTAC linker, enables the synthesis of PROTACs[1].

DBCO-PEG12-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.