n3-peg12-hydrazide

N3-PEG12-Hydrazide is a PEG-based linker for PROTACs, efficiently joining two essential ligands critical for PROTAC molecule formation. This linker facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

1-N-Boc-3-hydroxyazetidine (catalog number: T67084, CAS number: 141699-55-0) is a valuable organic compound used in life sciences research.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor used as a toxin payload in antibody-drug conjugates, is conjugated via a DBCO-(PEG)3-vc-PAB linker.

N-Boc-PEG-t-butyl ester is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation via the ubiquitin-proteasome system within cells.

Fmoc-N-amido-PEG-CH2COOH (MW 3400) is a PEG-based PROTAC linker used in PROTAC synthesis[1].

Fmoc-N-amido-PEG-CH2COOH (MW 5000), a PEG-based PROTAC linker, is used in PROTAC synthesis [1].

N-Succinimidyl 3-(Bromoacetamido)propionate is a PEG-based PROTAC linker used in the synthesis of PROTACs and antibody-drug conjugates (ADCs) [1, 2], serving as a cleavable ADC linker to facilitate drug-antibody conjugation for targeted delivery [2].