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nbi 35965 hydrochloride

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NBI 35965 hydrochloride
T869781782228-59-4
NBI 35965 hydrochloride is a selective CRF1 (corticotropin-releasing factor receptor 1) antagonist that is both orally active and capable of penetrating the brain. It possesses a K i value of 4 nM and a pK i of 8.5, and does not affect CRF2. This compound effectively diminishes CRF or stress-triggered ACTH (adrenocorticotropic hormone) production in vivo, demonstrating pIC 50 values of 7.1 and 6.9. Additionally, NBI 35965 hydrochloride exhibits anxiolytic properties [1] [2].
  • Inquiry Price
10-14 weeks
Size
QTY
NBI 35965 methanesulfonate 
T23058603151-83-3
NBI 35965 methanesulfonate  is a CRF1 antagonist.
  • $75
35 days
Size
QTY
NBI-27914 hydrochloride
T230571215766-76-9
corticotropin-releasing factor1 (CRF1) receptor antagonist
  • $540
35 days
Size
QTY
NBI-35965
T69544268546-19-6
NBI-35965 is a CRF1 receptor antagonist.
  • $2,120
8-10 weeks
Size
QTY