nh bis(peg4 c2 nh boc)

NH-bis(PEG4-C2-NH-Boc) is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH2-C2-NH-Boc (PROTAC Linker 22), an alkyl chain-based PROTAC linker, can be used in the synthesis of PROTACs.

1,2-Bis(2-iodoethoxy)ethane is a PEG-based PROTAC linker used in the synthesis of MT802 and SJF620, which are potent PROTAC BTK degraders with DC50s of 1 nM and 7.9 nM, respectively [1].

NH-bis(C1-Boc) is an uncleavable linker used for antibody-drug conjugates (ADC).

NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.

Boc-NH-PEG1-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

Bis-Tos-PEG4 (PROTAC Linker 16) is a PEG-based linker utilized in the synthesis of PROTACs.

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound used in the synthesis of PROTAC MG-277 [1].

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

NH2-C4-NH-Boc (compound 15) is a PROTAC linker of the Alkyl ether class, suitable for synthesizing various PROTAC molecules.

Cbz-NH-PEG12-C2-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands to form PROTAC molecules, thereby enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Cbz-NH-PEG5-CH2COOH is a PEG-based PROTAC linker used in PROTAC synthesis.

Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) is an E3 ligase ligand-linker conjugate.

Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-linker conjugate that incorporates the Thalidomide-based cereblon ligand and a linker[1].

Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.

Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-PEG11-OH, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-C12-NH2 is an alkyl ether-based PROTAC linker suitable for use in PROTAC synthesis.

Mal-PEG2-C2-Boc (Mal-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. Mal-PEG2-C2-Boc can be used in the synthesis of PROTACs.

Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Fmoc-NH-PEG10-acid, a PEG-based PROTAC linker, is utilized in the synthesis of PROTACs.

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a PROTAC BCL-XL degrader [1] [2].

Fmoc-NH-PEG8-NHS ester is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Cbz-NH-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs (Proteolysis Targeting Chimeras).

Cbz-NH-PEG1-CH2COOH, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Amino-PEG4-Boc is a PEG-based PROTAC linker suitable for use in PROTAC synthesis[1].

N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction [2].

Boc-NH-C4-acid is a PROTAC linker of the Alkyl ether class, utilized in the synthesis of PROTAC1 for the degradation of EED, EZH2, and SUZ12 in [PRC2].

Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker employed in PROTAC synthesis.

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Thalidomide-NH-CH2-COOH ((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)glycine) is a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.

Cbz-NH-PEG1-CH2CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis.

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker [PROTACs] useful in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.

t-Boc-N-amido-PEG4-NHS ester is a PEG derivative containing an NHS ester and a Boc-protected amino group. The NHS ester can be utilized to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.