nh2-peg3-c1-boc

NH2-PEG3-C1-Boc, also known as PROTAC Linker 5, is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

2-(2,6-dioxopiperidin-3-yl)-4-((7-hydrox is protac.

Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified derivative of Thalidomide serving as a Cereblon ligand to recruit CRBN proteins and a pivotal intermediate in the synthesis of CRBN-based PROTAC molecules for the targeted small molecule PROTACs aimed at SHP2 protein.

Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].

Boc-NH-C12-NH2 is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.

NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC).

NH2-C2-NH-Boc (PROTAC Linker 22) (PROTAC Linker 22) is a alkyl chain-based PROTAC linker. NH2-C2-NH-Boc can be used in the synthesis of PROTACs.

(S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker. (S,R,S)-AHPC-(C3- PEG) 2- C6- Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative containing a hydroxyl group and Boc-protected amino group, and is a PROTAC linker.

DBCO-(PEG)3-VC-PAB-MMAE is a chemical compound where monomethyl auristatin E (MMAE), a potent tubulin inhibitor acting as a toxin payload in antibody-drug conjugates, is conjugated to a DBCO-(PEG)3-vc-PAB linker.

Boc-NH-PEG1-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG11-CH2CH2N3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-PEG2-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH2-C5-NH-Boc (PROTAC Linker 23) (PROTAC Linker 23) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Boc-NH-PEG4-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG4-CH2CH2NH2 a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

NH2-C6-NH-Boc is a PROTAC linker. NH2-C6-NH-Boc can be used in the synthesis the Mcl-1 inhibitor based on PROTAC.

Boc-NH-C4-acid is a PROTAC linker belonging to the Alkyl/ether class, which can be used for the synthesis of PROTAC1 and can degrade EED, EZH2, and SUZ12 in PRC2.

Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1].

Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

C-NH-Boc-C-Bis-(C-PEG1-Boc) is a versatile alkyl/ether-based PROTAC linker for synthesizing PROTACs[1].

Mal-L-PA-NH-Boc, a noncleavable ADC linker, facilitates the synthesis of antibody-drug conjugates (ADCs).

Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in PROTAC synthesis[1].

PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Hydroxy-PEG4-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG4-(CH2)2-Boc can also be used in the synthesis of PROTAC.

Boc-NH-PEG1-Ph-O-CH2COOH is a PROTAC Linker which is used for the EED-targeted PROTAC[1].

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker for the development of proteolysis targeting chimeras (PROTACs)[1].

N-Boc-4-pentyne-1-amine is an alkyl chain-based PROTAC linker compound utilized in the synthesis of PROTAC MG-277[1].

S-(1-Hydroxy-2-methylpropan-2-yl) methanesulfonothioate, an ADC linker, is a glutathione cleavable compound used for the attachment of monoclonal antibodies (mAb) in antibody-drug conjugates (ADCs). It specifically refers to the Alkyl-Chain composition of the linker portion of these molecules [1].

Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.

NH-bis(PEG2-C2-Boc) is an alkyl/ether-based linker, utilized for the synthesis of PROTACs[1].

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.

Boc-NH-PEG4-Ms is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH-bis(PEG4-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH2-C4-NH-Boc (compound 15) is a PROTAC linker belonging to the Alkyl/ether class. NH2-C4-NH-Boc can be used to synthesize a series of PROTAC molecules.

Boc-NH-PEG10-CH2CH2NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-C1-PEG3-C3-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG15-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Biotin-PEG5-NH-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Boc-PEG4)-NH-PEG4-NH-Boc is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker, specifically designed for the synthesis of PROTACs [1].

NH2-PEG4-Lys(Boc)-NH-(m-PEG24) is a 28-unit polyethylene glycol (PEG) linker containing a cleavable bond, commonly employed in the production of antibody-drug conjugates (ADCs)[1].