nicotinamide, n(mdifluoromethoxyphenyl), hydrochloride

Nicotinamide, N-(m-difluoromethoxyphenyl)-, hydrochloride is a bioactive chemical.

Nicotinamide N-oxide (Nicotinamide 1-oxide) is recognized as an in vivo metabolite of nicotinamide which is a precurser of nicotinamide-adenine dinucleotide (NAD+) in animals. The enzyme that catalyzes the reduction of nicotinamide N-oxide to nicotinamide in the liver is xanthine oxidase.

N-Aminopiperidine hydrochloride (Piperidin-1-amine hydrochloride) is a metabolite (M1) of the canabinoid receptor 1 antagonist Rimonabant, an antiobesity agent.

N-(Hydroxymethyl)nicotinamide (Bilamid) is an antimicrobial agent.

N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo.

N-Nornuciferine hydrochloride(4846-19-9 free base) (N-Nornuciferine hydrochloride) is an aporphine alkaloid in lotus leaf, significantly inhibits CYP2D6 (IC50: 3.76 μM, Ki: 2.34 μM).

N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.

N-Noratherosperminine hydrochloride is alkaloid hydrochloride. Noratherosperminine has been extracted from Cryptocarya nigra.

N-Desethylsunitinib hydrochloride is a major and pharmacologically active metabolite of sunitinib, which is potent, ATP-competitive VEGFR, PDGFRβ, and KIT inhibitor.

(1S,4R)-N-DesmethylSertralineHydrochloride is a Serotonin transporter and Norepinephrine transporter inhibitor with IC50 of 19 nM and 35 nM, respectively.

GNF-8625 monopyridin-N-piperazine hydrochloride is a tropomyosin receptor kinase (TRK) inhibitor.

N-Desmethyltamoxifen hydrochloride is the primary metabolite of tamoxifen in humans.

N-Acetylputrescine is a polyamine commonly occurring excreted in normal human urine

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-morpholinoethyl)-, hydrochloride is a bioactive chemical.

N'-(2,4-Dimethylphenyl)-N-methylformimidamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64417 and the CAS number is 51550-40-4.

Acetamide, 2-(p-butoxyphenoxy)-N-(2-(dimethylamino)ethyl)-N-(m-ethoxyphenyl)-, hydrochloride is a bioactive chemical.

N-Desmethyl clozapine-d8 Hydrochloride is a deuterated compound of N-Desmethyl clozapine Hydrochloride. N-Desmethyl clozapine Hydrochloride has a CAS number of 1189888-77-4.

N-Desmethyl Clomipramine hydrochloride is a primary plasma N-desmethyl Clomipramine metabolite .

(S)-N-(1-Amino-5-guanidino-1-oxopentan-2-yl)benzamide hydrochloride, with catalog number T65350 and CAS number 4299-03-0, is a valuable organic compound used in life sciences research.

(R)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T64535.

2-Amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66533 and the CAS number is 1171331-39-7.

N-(3-Fluorophenyl)piperidin-4-amine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67608 and the CAS number is 923565-91-7.

N-Demethylvancomycin is a glycopeptide antibiotic that has been found inNocardia orientalis.1It is active against several strains ofS. aureusandS. epidermidisin vitroandin vivo.2Formulations containing N-demethylvancomycin have been used in the treatment of bacterial infections. 1.Boeck, L.D., Mertz, F.P., Wolter, R.K., et al.N-demethylvancomycin, a novel antibiotic produced by a strain of Nocardia orientalis. Taxonomy and fermentationJ. Antibiot. (Tokyo)37(5)446-453(1984) 2.Hunt, A.H., Marconi, G.G., Elzey, T.K., et al.A51568A: N-demethylvancomycinJ. Antibiot. (Tokyo)37(8)917-919(1984)

N-Demethyl Ivabradine D6 Hydrochloride salt is the deuterium labeled N-Demethyl Ivabradine, which is a Ivabradine metabolite.

Benzylamine, m-chloro-N-(2-chloroethyl)-N-ethyl-, hydrochloride is a bioactive chemical.

Isonicotinamide, N-(3-difluoromethoxyphenyl)-, hydrochloride is a bioactive chemical.

N-(3-((4-Amino-6,7-dimethoxyquinazolin-2-yl)(methyl)amino)propyl)furan-2-carboxamide hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T66667.

N-Methyldopamine hydrochloride, a modified version of dopamine (DA) that maintains agonist activity at the DA1 receptor, serves as an adrenaline precursor in the adrenal medulla. It retains the capability for universal surface coating and undergoes secondary reactions via surface catechols. This compound is utilized in heart failure research [1] [2] [3].

N-Desethyl Sunitinib (SU-12662) (hydrochloride), a metabolite of sunitinib, is a robust ATP-competitive inhibitor of VEGFR, PDGFRβ, and KIT, with inhibition constants (K i values) of 2, 9, 17, 8, and 4 nM for VEGFR-1, -2, -3, PDGFRβ, and KIT, respectively [1].

Fluphenazine is a traditional antipsychotic compound that tightly binds the dopamine D2 receptor (Ki = 0.55 nM) and also reversibly inhibits calmodulin at micromolar concentrations. Fluphenazine-N-2-chloroethane is a derivative of fluphenazine that contains an alkylating chlorethylamine chain, which produces irreversible protein binding. It is a relatively selective, irreversible antagonist of D2 receptors both in vitro (IC50 = 100 nM) and in vivo, inactivating approximately 90% of D2 receptors in mice within 4 hours of treatment. Through this action, fluphenazine-B-2-chloroethane can be used to induce catalepsy in mice. It irreversibly inhibits calmodulin at higher doses (IC50 = 10 μM), which can sensitize cancer cells to TRAIL-induced apoptosis.

Propiverine N-oxide (hydrochloride) is the major metabolite of propiverine in human plasma or urine.

N-CBZ-Phe-Arg-AMC hydrochloride (N-CBZ-Phe-Arg-AMC hydrochloride (65147-22-0 Free base)) is a cysteine peptidase and serine protease substrate that can be used to assess cysteine peptidase and serine protease activity.

High affinity κ agonist

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(diethylamino)ethyl)-, hydrochloride is a bioactive chemical.

N,N-Bis(2-chloroethyl)aniline hydrochloride is a bioactive chemical.

2-(Diethylamino)-N-(2,5-dimethylphenyl)acetamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67146 and the CAS number is 1012864-23-1.

N-methyl-2-HOBA is a methylated form of the isoketal scavenger 2-HOBA .1It has low reactivity with isoketals and has no effect on hypertension induced by angiotensin II . N-methyl-2-HOBA has been used as a negative control for the activity of 2-HOBA in a mouse model of hypertension. 1.Kirabo, A., Fontana, V., de Faria, A.P.C., et al.DC isoketal-modified proteins activate T cells and promote hypertensionJ. Clin. Invest.124(10)4642-4656(2014)

N-(2-Hydroxyethyl)nicotinamide is a useful organic compound for research related to life sciences. The catalog number is T65332 and the CAS number is 6265-73-2.

Nicotinamide Hydrochloride, a form of vitamin B3 (niacin), inhibits sirtuin 2 (SIRT2) activity in vitro with an EC50 of 2 μM, reducing melanoma cell number by up to 90% and increasing cellular NAD+, ATP, and ROS levels. It also inhibits tumor growth in vivo and improves survival in melanoma-bearing mice, making it useful for skin cancer research, including melanoma.

N-β-Alanyldopamine hydrochloride (NBAD hydrochloride) represents the primary dopamine derivative found in haemolymph [1].

N-piperidine Ibrutinib hydrochloride is a potent BTK inhibitor, a BTK ligand, inhibits WT BTK and C481S BTK, which can be used to synthesize a range of PROTAC molecules.N-piperidine Ibrutinib hydrochloride has potential anticancer N-piperidine Ibrutinib hydrochloride has potential anticancer activity, inhibiting the growth and proliferation of cancer cells.

N-Methyl Duloxetine hydrochloride elicits both tonic and use-dependent block of neuronal Na+ channels. N-Methyl Duloxetine hydrochloride is an analgesic.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-piperidinoethyl)-, hydrochloride is a bioactive chemical.

N-(4-(2-Aminoacetyl)-5-methoxy-2-phenoxyphenyl)methanesulfonamide hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66231 and the CAS number is 149436-41-9.

3-Chloro-N-methylpropan-1-amine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65367 and the CAS number is 97145-88-5.

Nicotinamide, N-(2-pyridyl)- is a biochemical.

Acetamide, N-(m-anisyl)-2-(p-butoxyphenoxy)-N-(2-(1-pyrrolidinyl)ethyl)-, hydrochloride is a bioactive chemical.

Formulation product; absorption enhancer

2-Chloro-N,N-dimethylpropan-1-amine hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65980 and the CAS number is 4584-49-0.

N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.