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nsc-115829

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Tretazicar
5-Aziridino-2,4-dinitrobenzamide,CB1954,NSC 115829
T679821919-05-1
CB1954(Tretazicar (NSC-115829)), an anticancer prodrug, is activated by NAD(P)H quinone oxidoreductase 2. It is converted in the presence of the enzyme NQO2 and co-substrate caricotamide ( EP-0152R) (EP) into a potent cytotoxic bifunctional alkylating agent.
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