nvp cxcr2 20

NVP CXCR2 20 is an effective selective CXCR2 antagonist (IC50 = 40 nM) with oral bioavailability.

NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9 CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1 CycB, CDK2 CycA and CDK16 CycY kinases (IC5

pregn-2-en-20-yl acetate is a useful organic compound for research related to life sciences and the catalog number is T131420.

3-O-(2'E,4'E-decadienoyl)-20-O-acetylingenol is an important organic compound for life sciences research [Catalog No. T124827, CAS No. 466663-12-7].

CXCR2 antagonist 2 is a potent CXCR2 antagonist for cancer immunotherapy, exhibiting an IC50 value of 95 nM.

2-O-Acetyl-20-hydroxyecdysone is an ecdysone present in insects and terrestrial plants. 2-O-Acetyl-20-hydroxyecdysone inhibits amyloid-β42-induced cytotoxicity and is able to reduce the formation of Aβ oligomers by promoting fibrillogenesis, which converts Aβ oligomers into less toxic fibers.

20)abeotaxa-4(20),11-dien-10-one'>2alpha,7beta,13alpha-Triacetoxy-5alpha-cinnamoyloxy-9beta-hydroxy-2(3->20)abeotaxa-4(20),11-dien-10-one is a natural product for research related to life sciences. The catalog number is TN2840 and the CAS number is 322471-42-1.

3-O-(2'E ,4'Z-decadienoyl)-20-deoxyingenol is a useful organic compound for research related to life sciences and the catalog number is T124424.

VEGFR-2-IN-20 (Compound 7) is a potent VEGFR inhibitor with significant potential for cancer research [1].

SARS-CoV-2-IN-20 (Compound 1a) is a highly effective SARS-CoV-2 inhibitor with an impressive EC50 value of 6.5 μM, demonstrating significant potential for advancing infectious disease research [1].

COX-2-IN-20 (Compound 5d) is a selective and orally active COX-2 inhibitor (IC50 = 17.9 nM) with anti-inflammatory activity [1].

3-O-(2'E ,4'Z-decadienoyl)-20-O-acetylingenol is a useful organic compound for research related to life sciences and the catalog number is T125709.

(R,R)-CXCR2-IN-2, a diastereoisomer of CXCR2-IN-2 (compound 68), is a brain-penetrant CXCR2 antagonist with a pIC50 of 9 in the Tango assay and 6.8 in the HWB Gro-α induced CD11b expression assay[1].

CXCR2-IN-2 is a selective CXCR2 antagonist that is brain penetrant and orally bioavailable, with IC50 values of 5.2 nM and 1 nM in the β-arrestin assay and CXCR2 Tango assay, respectively. It exhibits approximately 730-fold selectivity over CXCR1 and greater than 1900-fold selectivity over all other chemokine receptors. Furthermore, CXCR2-IN-2 effectively inhibits Gro-α induced CD11b expression in human whole blood, displaying an IC50 of 0.04 μM[1].

SARS-CoV-2 3CLpro-IN-20 is a covalent inhibitor of SARS-CoV-2 3CLpro with an IC50 of 0.43 μM and potential antiviral activity.