nw-propyl-l-arginine

Highly selective and potent inhibitor of nNOS (Ki = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo. Kakoki et al (2001) The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 281 R91 PMID:11404282 |Zhang et al (1997) Potent and selective inhibition of neuronal nitric oxide synthase by Nω-propyl-L-arginine. J.Med.Chem. 40 3869 PMID:9397167

L-Arginine hydrochloride is a nitrogen donor for synthesis of nitric oxide.

1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate lymphocyte proliferation through an interleukin-2-independent pathway. 4. A combination of oral L-citrulline and L-Arginine effectively and rapidly augments NO-dependent responses at the acute stage.

N-Acetyl-L-arginine (Ac-Arg-OH), an N-acyl-L-alpha-amino acid with a strong basic nature (based on its pKa), has elevated serum levels in hyperargininemic patients and is associated with several diseases, including uremia and colorectal cancer. In untreated hyperargininemic patients, it reaches its highest levels in cerebrospinal fluid. It has also been detected in apples and loquats, suggesting it could be a potential biomarker for consumption of these foods. Additionally, a low-arginine diet combined with sodium benzoate therapy leads to a marked decrease in plasma N-acetyl-L-arginine concentrations.

Nω-Hydroxy-nor-L-Arginine Dihydrochloride is a competitive and reversible inhibitor of arginase

N-Acetyl-L-arginine dihydrate (N-Ac-L-arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population.

Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM. It exhibits a remarkable 149-fold selectivity for nNOS over endothelial NOS (eNOS).

N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine is a useful organic compound for research related to life sciences. The catalog number is T65254 and the CAS number is 50913-12-7.

NG,NG-dimethyl-L-Arginine dihydrochloride is an endogenous nitric oxide synthase inhibitor. Nitric oxide (NO) that is synthesised from L-arginine contributes to the regulation of blood pressure and to host defence[1].

N2-Boc-L-arginine Hydrochloride Hydrate is a useful organic compound for research related to life sciences. The catalog number is T65690 and the CAS number is 114622-81-0.

(2,4-Dinitrophenyl)-L-arginine is a useful organic compound for research related to life sciences. The catalog number is T64447 and the CAS number is 1602-42-2.

L-Leucyl-L-prolyl-L-prolyl-L-seryl-L-arginine is a peptide.

Benzoyl-L-arginine is a useful organic compound for research related to life sciences. The catalog number is T65772 and the CAS number is 154-92-7.

L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in hypertension research [1].

Nω-allyl-L-arginine is a competitive and reversible inhibitor of bovine brain nitric oxide synthase (nNOS), inactivating nNOS efficiently over time. It also serves as a substrate, producing L-arginine, acrolein, and H2O.

L-hydroxy Arginine is a substrate for nitric oxide synthase in the catabolism of L-arginine to form nitric oxide. It has been used as a biomarker for reduced nitric oxide formation in patients with cardiovascular disease and metabolic syndrome.

Selective L-arginine uptake inhibitor

L-Arginine-15N4 ((S)-(+)-Arginine-15N4) hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vasodilator is crucial, especially during a sickle cell crisis where its levels are notably diminished.

Phospho-L-arginine is a phosphorylated form of L-arginine and a highly diffusible, high-energy metabolite and phosphagen involved in energy storage in invertebrates including crustaceans, insects, and Trypanosoma species. In the locust L. migratoria, phospho-L-arginine is found in the flight muscles, where it acts as both a buffer system and shuttle mechanism for high-energy phosphate. Measurement of phospho-L-arginine by 31P-NMR spectroscopy has been used to study invertebrate energy metabolism in vivo.

N2-(tert-Butoxycarbonyl)-Nw-nitro-L-arginine is a useful organic compound for research related to life sciences. The catalog number is T65255 and the CAS number is 2188-18-3.

[8-L-arginine] deaminovasopressin (dAVP) is a vasopressin analog [1].

DL-Arginine is deployed in the study of amino acid complexation dynamics and the formation of crystal structures.

DL-Arginine xhydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66618 and the CAS number is 32042-43-6.