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  • E3 Ligase Ligand-Linker Conjugate
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Results for "

o benzylhydroxylamine (hydrochloride)

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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O-Benzylhydroxylamine (hydrochloride)
T380202687-43-6
O-Benzylhydroxylamine is a building block.1,2It has been used in the synthesis of β-lactam inhibitor precursors and fluoroquinolone derivatives with antibiotic activity. 1.Bellettini, J.R., and Miller, M.J.A short synthesis of an important precursor to a new class of bicyclic β-lactamase inhibitorsTetrahedron Lett.38(2)167-168(1997) 2.Asadipour, A., Moshafi, M.H., Khosravani, L., et al.N-substituted piperazinyl sarafloxacin derivatives: synthesis and in vitro antibacterial evaluationDaru.26(2)199-207(2018)
  • $123
35 days
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O-Acetyl-L-serine hydrochloride
T472266638-22-0
O-Acetylserine (OASS) is an acylated amino acid derivative. It is an intermediate in the biosynthesis of the common amino acid cysteine in bacteria and plants. Its presence in humans arises from either microbial metabolism in the gut or through consumptio
  • $50
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Thalidomide-O-amido-C6-NH2 hydrochloride
T188162376990-31-5
Thalidomide-O-amido-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, integrating a Thalidomide-based cereblon ligand with a linker, suitable for PROTAC synthesis.
  • $54
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Thalidomide-O-C4-NH2 hydrochloride
T94022376990-29-1
Thalidomide-linker 9 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
  • $31
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Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
T188192376990-30-4
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride, incorporating an E3 ligase ligand and a linker, can be used as an immunomodulator for the treatment of cancer.
  • $30
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Thalidomide-O-C6-NH2 hydrochloride
T400312245697-88-3
Thalidomide-O-C6-NH2 hydrochloride (4-((6-aminohexyl)oxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride) is a synthesized E3 ligase ligand-linker conjugate.
  • $39
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O-1057 hydrochloride
T69848216988-51-1
O-1057 hydrochloride is a water-soluble cannabinoid receptor agonist with antinociceptive properties. RESEARCH USE ONLY.
  • $1,820
8-10 weeks
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O-desmethyl Brinzolamide (hydrochloride)
T37403
O-desmethyl Brinzolamide is an active metabolite of the carbonic anhydrase (CA) inhibitor brinzolamide .1,2It inhibits CAII and CAIV (IC50s = 0.136 and 165 nM, respectively).1 1.Huang, Q., Rui, E.Y., Cobbs, M., et al.Design, synthesis, and evaluation of NO-donor containing carbonic anhydrase inhibitors to lower intraocular pressureJ. Med. Chem.58(6)2821-2833(2015) 2.Lo Faro, A.F., Tini, A., Gottardi, M., et al.Development and validation of a fast ultra-high-performance liquid chromatography tandem mass spectrometry method for determining carbonic anhydrase inhibitors and their metabolites in urine and hairDrug Test Anal.13(8)1552-1560(2021)
  • $67
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Thalidomide-5-O-C10-NH2 hydrochloride
T77957
Thalidomide-5-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1].
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Thalidomide-5-O-C12-NH2 hydrochloride
T77959
Thalidomide-5-O-C12-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, when linked to a ligand for protein, forms PROTACs [1].
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5-Amino-2’-deoxy-2’-O-methyluridine hydrochloride
TNU0412
Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Amino nucleosides; 2’-Modified nucleosides
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7-10 days
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Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
T188202245697-84-9
Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, incorporates a cereblon ligand derived from Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology, which utilizes small molecules to induce protein degradation [1].
  • Inquiry Price
7-10 days
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Methyl O-(tert-butyl)-L-threoninate hydrochloride
T6524771989-43-0
Methyl O-(tert-butyl)-L-threoninate hydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65247 and the CAS number is 71989-43-0.
    7-10 days
    Inquiry
    Thalidomide-O-amido-C4-NH2 hydrochloride
    T188152245697-86-1
    Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand derived from Thalidomide with a linker and is commonly used in the synthesis of PROTACs[1].
      Inquiry
      O-Demethyl Lenvatinib hydrochloride
      T74021
      O-Demethyl Lenvatinib hydrochloride, a metabolite of Lenvatinib (E7080), is an orally administered multi-targeted tyrosine kinase inhibitor. It targets and inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating potent antitumor activities [1] [2].
      • $82
      5 days
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      O-Desmethyl Brinzolamide hydrochloride
      T870552967475-56-3
      • Inquiry Price
      10-14 weeks
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      Thalidomide-O-amido-C8-NH2 hydrochloride
      T18817
      Thalidomide-O-amido-C8-NH2 hydrochloride is a synthetic conjugate of an E3 ligase ligand-linker, which combines a cereblon ligand derived from Thalidomide and a linker. It can be utilized in the synthesis of PROTACs[1].
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      O-2,3’-Anhydro-5-methylcytidine   hydrochloride
      TNU151551391-96-9
      O-2,3'-Anhydro-5-methylcytidine hydrochloride is a Nucleoside Derivative - 3'-Modified nucleoside.
      • Inquiry Price
      7-10 days
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      Thalidomide-O-C5-NH2 hydrochloride
      T400792419145-66-5
      Thalidomide-O-C5-NH2 hydrochloride is a synthetic compound consisting of a ligand-linker conjugate with E3 ligase activity. It combines a cereblon ligand based on Thalidomide and a linker commonly utilized in PROTAC technology.
        Inquiry
        Thalidomide-4-O-C7-NH2 hydrochloride
        T77917
        Thalidomide-4-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, plays a role in the recruitment of CRBN protein and, when linked to a protein ligand, forms PROTACs [1].
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        Thalidomide-5-O-C8-NH2 hydrochloride
        T77955
        Thalidomide-5-O-C8-NH2 hydrochloride is a Thalidomide-based cereblon ligand that recruits CRBN protein and, when connected to a ligand via a linker, forms PROTACs [1].
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        Thalidomide-5-O-C9-NH2 hydrochloride
        T77956
        Thalidomide-5-O-C9-NH2 hydrochloride, a thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be tethered to a protein ligand via a linker, enabling the formation of PROTACs [1].
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        Thalidomide-5-O-C11-NH2 hydrochloride
        T77958
        Thalidomide-5-O-C11-NH2 hydrochloride, a thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].
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        Thalidomide-5-O-C13-NH2 hydrochloride
        T77960
        Thalidomide-5-O-C13-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It is designed to conjugate with a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].
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        Thalidomide-4-O-C14-NH2 hydrochloride
        T77964
        Thalidomide-4-O-C14-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and, through the attachment of a linker, can be utilized to create PROTACs [1].
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        Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
        T188222245697-85-0
        Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating the Thalidomide-based cereblon ligand and a linker.
        • $49
        5 days
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        O-4-Methoxybenzoylepilupinine hydrochloride
        T131468
        O-4-Methoxybenzoylepilupinine hydrochloride is a useful organic compound for research related to life sciences and the catalog number is T131468.
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        O-Demethyldeacetyldiltiazem hydrochloride
        T33781L102281-01-6
        O-Demethyldeacetyldiltiazem hydrochloride is a biochemical.
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        Thalidomide-4-O-C10-NH2 hydrochloride
        T77919
        Thalidomide-4-O-C10-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of the CRBN protein. This compound can be conjugated with a protein ligand via a linker to synthesize PROTACs [1].
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        Thalidomide-5-O-C3-NH2 hydrochloride
        T779502694727-94-9
        Thalidomide-5-O-C3-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment and can be conjugated to a protein ligand via a linker to synthesize PROTACs [1].
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        Thalidomide-5-O-C5-NH2 hydrochloride
        T779522761385-94-6
        Thalidomide-5-O-C5-NH2 hydrochloride, a Thalidomide-derived cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to form PROTACs [1].
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        Thalidomide-5-O-C6-NH2 hydrochloride
        T779532761398-05-2
        Thalidomide-5-O-C6-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to another ligand to form proteolysis-targeting chimeras (PROTACs) [1].
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        Thalidomide-5-O-C7-NH2 hydrochloride
        T77954
        Thalidomide-5-O-C7-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates CRBN protein recruitment. This compound can be tethered to a protein-targeting ligand using a linker, enabling the formation of PROTACs [1].
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        O-Desmethyl Mebeverine alcohol hydrochloride
        T75423856620-39-8
        O-Desmethyl Mebeverine Alcohol Hydrochloride, a potent metabolite of Mebeverine, functions as an α1 receptor (repector) inhibitor, facilitating the relaxation of the gastrointestinal tract.
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        Thalidomide-O-C8-NH2 hydrochloride
        T402612636798-38-2
        Thalidomide-O-C8-NH2 hydrochloride is a chemical compound consisting of a synthesized E3 ligase ligand-linker conjugate. This compound incorporates a cereblon ligand derived from Thalidomide, as well as a linker employed in PROTAC technology.
        • $490
        35 days
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        O-2545 hydrochloride
        T84516874745-43-4
        O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.
        • Inquiry Price
        8-10 weeks
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        O-desmethyl Mebeverine acid D5 hydrochloride
        T19490
        O-desmethyl Mebeverine acid D5 hydrochloride is the deuterium labeled O-desmethyl Mebeverine acid.
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        Thalidomide-5-O-C2-NH2 hydrochloride
        T779492694727-89-2
        Thalidomide-5-O-C2-NH2 hydrochloride, a Thalidomide-based cereblon ligand, facilitates the recruitment of CRBN protein and can be conjugated via a linker to form PROTACs [1].
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        Thalidomide-5-O-C4-NH2 hydrochloride
        T779512694727-93-8
        Thalidomide-5-O-C4-NH2 hydrochloride, a cereblon ligand derived from Thalidomide, facilitates the recruitment of CRBN protein. It can be tethered to a ligand for protein recruitment through a linker, enabling the formation of PROTACs [1].
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        Thalidomide-4-O-C11-NH2 hydrochloride
        T77962
        Thalidomide-4-O-C11-NH2 hydrochloride is a thalidomide-based cereblon ligand for CRBN protein recruitment, capable of conjugation to a protein ligand via a linker to create PROTACs [1].
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        Thalidomide-4-O-C12-NH2 hydrochloride
        T77963
        Thalidomide-4-O-C12-NH2 hydrochloride is a cereblon ligand derived from Thalidomide, used to recruit the CRBN protein. It can be linked to a protein ligand via a linker, facilitating the creation of PROTACs [1].
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        Thalidomide-5-O-C14-NH2 hydrochloride
        T77961
        Thalidomide-5-O-C14-NH2 hydrochloride, a cereblon ligand based on Thalidomide, facilitates the recruitment of CRBN protein. By incorporating a linker, this compound can be conjugated to a ligand to create PROTACs [1].
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        Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
        T188182204226-02-6
        Thalidomide-O-amido-PEG-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate, incorporating a Thalidomide-based cereblon ligand and a linker. This compound is used in the synthesis of PROTACs.
        • $51
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        O-desmethyl Mebeverine acid
        T11988586357-02-0
        O-desmethyl Mebeverine acid is a metabolite of Mebeverine.
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        O-Desmethyl Mebeverine acid-d5
        T194911329488-46-1
        O-desmethyl Mebeverine acid D5 is the deuterium labeled O-desmethyl Mebeverine acid.
        • $428
        7-10 days
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