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  • Apoptosis
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Results for "ono 4059" in TargetMol Product Catalog
  • Inhibitor Products
    3
    TargetMol | Activity
Tirabrutinib hydrochloride
T123111439901-97-9
Tirabrutinib hydrochloride (GS-4059 (hydrochloride)) is a selective and novelBTK with IC50 2.2 nm inhibitor.
  • $30
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Tirabrutinib
TQ02361351636-18-4
Tirabrutinib (GS-4059) (ONO-4059) is an orally active Bruton’s Tyrosine Kinase (Btk) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to Btk and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies.
  • $39
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ONO-4059 analog
T69211351635-67-0
ONO-4059 analog (ONO-WG-307)ue is an analogue of ONO-4059, which is a highly potent and selective oral BTK inhibitor with IC50 of 23.9 nM. Phase 1.
  • $38
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