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By Target- Apoptosis
- TOPK(2)
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Results for "
ots 514 hydrochloride
" in TargetMol Product Catalog- Inhibitor Products2
OTS514 hydrochloride
T41342319647-76-0
OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).
- $56
Size
QTY
OTS514
T4134L1338540-63-8
OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor. OTS514 exhibits a growth-suppressive effect on small cell lung cancer. OTS514 effectively suppressed the growth of SCLC cell lines (IC50: 0.4 ~ 42.6 nM). Treatment with OTS514 suppressed forkhead box protein M1 (FOXM1) activity. OTS514 treatment reduced CD90-positive SCLC cells and showed a higher cytotoxic effect against lung sphere-derived CSC-like SCLC cells.
- $89
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