oxybutynin r-isomer hcl

Oxybutynin R-isomer , also known as Aroxybutynin, is a muscarinic receptor antagonist. Aroxybutynin is the optically avtice inhibitor of proliferation and supresses gene expression in bladder smooth muscle cells. Oxybutynin exerts direct antispasmodic effect on smooth muscle and inhibits the muscarinic action of acetylcholine on smooth muscle. It exhibits one-fifth of the anticholinergic activity of atropine on the rabbit detrusor muscle, but four to ten times the antispasmodic activity. No blocking effects occur at skeletal neuromuscular junctions or autonomic ganglia (antinicotinic effects).

(R,R)-DuP 747-HCl is a Dup 747 derivative.

(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord.

MKC-963 is a platelet aggregation inhibitor and autoinducer of CYP3A4.

Midodrine is a vasopressor/antihypertensive agent for the treatment of symptomatic postural hypotension.

(R)-Nepicastat HCl (RS-25560-198 HCl), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

BAY-6035 is an inhibitor of the methylation of MEKK2 peptide.

INCB3344 is a potent CCR2 antagonist. INCB3344 R-isomer is the R-isomer of INCB3344.

(R)-SCH-23982 HCl is a [125I]-(R)-SCH-23982 precursor and a D1 antagonist.

BAY-598 R-isomer is the R-isomer of BAY589, which is used as a reference compound. It is is an inhibitor of lysine N-methyltransferase (SMYD2) and is selective for SMYD2 over protease-activated receptor 1 (PAR1).

(R)-Oxybutynin (Aroxybutynin) is an orally active muscarinic receptor antagonist, which exhibits antimuscarinic, antispasmodic, and anticholinergic activity. This compound, being the (R)-isomer of Oxybutynin, competitively antagonizes Carbachol-induced contractions. It is particularly useful in researching neurogenic bladder dysfunction-related incontinence [1] [2] [3].

R(+)-SKF-38393A is a D1 dopamine receptor agonist and also is a more active enantiomer of (±)-SKF-38393A.

R-Verapamil-d7 HCL is a deuterated compound of R-Verapamil HCL. R-Verapamil HCL has a CAS number of 1188265-55-5.

(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an inhibitor of P-Glycoprotein.

Verapamil hydrochloride (Verapamil HCl) is a calcium channel blocker that is a class IV anti-arrhythmia agent.

S-Verapamil-d7 HCL is a deuterated compound of S-Verapamil HCL. S-Verapamil HCL has a CAS number of 1188265-55-5.

(S)-Verapamil hydrochloride is an inhibitor of leukotriene C4 (LTC4) and calcein transport by MRP1,and leads to the death of potentially resistant tumor cells.

(+/-)-Verapamil hydrochloride-d7 is a deuterated compound of (+/-)-Verapamil hydrochloride. (+/-)-Verapamil hydrochloride has a CAS number of 152-11-4. Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.

Verapamil (CP-16533-1) is a calcium channel blocker and an orally active and effective inhibitor of P-gp. Verapamil inhibits CYP3A4 and can be used in studies about the treatment of high blood pressure, heart arrhythmias, and angina research.