p19, inhibits cdk4

4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.

[D-Pro4,D-Trp7,9,10] Substance P (4-11) serves as a potent antagonist of the tachykinin family of neuropeptides [1].

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent antagonist to Substance P, significantly reducing plasma aldosterone (ALDO) concentrations[1].

Substance P(1-4) acts as a potent antagonist of neurokinin receptors (NK-R) and regulates normal hematopoiesis, additionally inhibiting the formation of endogenous erythroid colonies (EEC) [1].

[Tyr(P)4] Angiotensin II is a peptide that exerts a multitude of effects on vascular smooth muscle. These effects include the contraction of normal arteries, as well as the induction of hypertrophy or hyperplasia in cultured cells or diseased vessels.

4''-O-trans-p-Coumaroylafzelin is a natural product for research related to life sciences. The catalog number is TN6121 and the CAS number is 623927-14-0.

4-O-D-Glucopyranosyl-p-coumaric acid is a useful organic compound for research related to life sciences. The catalog number is T126288 and the CAS number is 117405-49-9.

N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) acts as an agonist for lysosomal acid α-glucosidase (GAA). It dose-dependently enhances intracellular GAA activities in Pompe disease patient fibroblasts harboring the M519V mutation [1].

2'',4''-Di-O-(Z-p-coumaroyl)afzelin is a natural product for research related to life sciences. The catalog number is TN2712 and the CAS number is 205534-17-4.

Butyraldehyde, 4-(p-aminophenoxy)-, diethyl acetal is a bioactive chemical.

(p-Iodo-Phe7)-ACTH (4-10), a derivative of adrenocorticotrophic hormone (ACTH) produced by the anterior pituitary gland, functions as a melanocortin (MC) receptor antagonist. It effectively inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats [1].

Substance P (4-11), a C-terminal fragment of Substance P, acts as a highly selective agonist for NK1 receptors, demonstrating specificity in its interaction.

[Sar4] Substance P (4-11) is a Substance P agonist and an analog of the C-terminus fragment of Substance P, known as Substance P (4-11) [1].

Ammonium, (4-(p-ethyldimethylammoniophenyl)butyl)ethyldimethyl-, diiodide can be used in related research in the field of life sciences. Its product number is T30012 and CAS number is 63981-94-2.

8alpha-Hydroxylabda-13(16),14-dien-19-yl p-hydroxycinnamate is a natural product for research related to life sciences. The catalog number is TN3283 and the CAS number is 117254-98-5.

Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6304 and the CAS number is 71781-79-8.

m-Toluidine, alpha-((p-chlorophenyl)sulfonyl)-4-(octyloxy)- is a bioactive chemical.

4-Chloro-5-(p-tolyl)-1H-imidazole-2-carbonitrile is a useful organic compound for research related to life sciences and the catalog number is T66379.

4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T64550 and the CAS number is 1061214-06-9.

FGTI-2734 mesylate, a RAS C-terminal mimetic compound with dual farnesyl transferase (FT) and geranylgeranyl transferase-1 (GGT) inhibitory activities (IC50s of 250 nM and 520 nM for FT and GGT, respectively), mitigates KRAS resistance by preventing its membrane localization, effectively impeding mutant KRAS patient-derived pancreatic tumors.

[DAla4] Substance P (4-11), an analog of Substance P (Substance P), effectively inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin) and 125I-Bolton Hunter-conjugated Substance P to rat brain cortex membranes, with IC50 values of 0.5 μM and 0.15 μM, respectively [1].

Antimicrobial agent.

4-(p-Biphenylyl)-3-hydroxybutyric acid is a useful organic compound for research related to life sciences and the catalog number is T124405.

m-Anisidine, 4-((5-p-tolylpentyl)oxy)- is a Drug / Therapeutic Agent.

Acetophenone, 4'-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.

Acetanilide, 4'-(5-(p-(dimethylamino)phenoxy)pentyloxy)-N-ethyl- is a bioactive chemical.

2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio-D-ribofuranose is a Carbohydrate Derivative.

Benzamide, N-(4-(p-aminophenoxy)butyl)- is a bioactive chemical.

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-2-O-acetyl-5-(O-p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1038.

Super-chelating agent & MRI contrast agent

Nucleoside Derivatives - 2’-Modified nucleosides, 7-Deaza-purine nucleosides, Halo-nucleosides

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1024.

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin is a natural product for research related to life sciences. The catalog number is TN2871 and the CAS number is 349545-02-4.

P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM. P-gp inhibitor 4 increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells .

19-Nor-4-hydroxyabieta-8,11,13-trien-7-one is a useful organic compound for research related to life sciences and the catalog number is T124620.

m-Anisidine, 4-((5-(p-nitrophenyl)pentyl)oxy)- is a bioactive chemical.

Ammonium, (4-(p-trimethylammoniophenyl)butyl)trimethyl-, diiodide is a bioactive chemical.

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1021.

Nucleoside Derivatives - 7-Deaza-8-aza-purine nucleosides; 6-Modified purine nucleosides

Glycolanilide, 4'-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.

3'',4''-Di-O-p-coumaroylquercitrin is a natural product for research related to life sciences. The catalog number is TN5487 and the CAS number is 437615-43-5.

m-Anisidine, 4-((5-((p-chlorophenyl)thio)pentyl)oxy)- is a bioactive chemical.

Substance P (1-4) is a substance P N-terminal tetrapeptide fragment.

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing their effects [1].

m-Toluidine, 4-(octyloxy)-alpha-(p-tolylsulfonyl)- is a bioactive chemical.

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin has a wide range of applications in life science related research.

m-Anisidine, 4-((p-(methylsulfonyl)benzyl)oxy)- is a bioactive chemical.

4'-O-trans-p-Coumaroylmussaenoside is a natural product of Callicarpa, Verbenaceae. The catalog number is TN3065 and the CAS number is 1246012-27-0. 4'-O-trans-p-Coumaroylmussaenoside can be used as a reference standard.

Benzoic acid, p-(methylsulfonyl)-, ester with 2,2-dichloro-4'-hydroxy-N-methylacetanilide is a bioactive chemical.