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(6)
By Target- Bcr-Abl
- PROTACs(1)
- Src(1)
- c-Kit(1)
- Others(6)
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Results for "
p210bcr/abl
" in TargetMol Product Catalog- Inhibitors & Agonists14
- PROTAC Products1
BCR-ABL-IN-4
T639322669790-59-2
BCR-ABL-IN-4 is a BCR-ABL inhibitor exhibiting anticancer activity with an inhibitory effect on cancer cell growth, specifically on K562 cells (IC50: 0.67 nM) and BCR-ABL T315I-transfected Ba F3 cells (IC50: 16 nM).
- $1,520
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QTY
PROTAC BCR-ABL Degrader-1
T77974
PROTAC BCR-ABL Degrader-1 (compound PROTAC 1), featuring a 2-oxoethyl linker, induces Bcr-Abl degradation via the ubiquitin-proteasome pathway and exhibits antiproliferative effects on K562 cells, indicating its potential in cancer research [1].
- Inquiry Price
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BCR-ABL-IN-3
T397322240191-12-0
BCR-ABL-IN-3 is a highly effective, irreversible inhibitor of Bcr-Abl, with an IC50 value of ≤100 nM for Ba F3 Bcr-Abl T3151, displaying significant anti-cancer activity.
- $970
Size
QTY
BCR-ABL-IN-2
T10489897369-18-5
BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).
- $1,520
Size
QTY
BCR-ABL-IN-1
T10488188260-50-6
BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.
- $1,520
Size
QTY
BCR-ABL kinase-IN-3
T858152699634-21-2
BCR-ABL kinase-IN-3 (example 1), a potent BCR-ABL inhibitor, is significant in the study of acute myeloid leukemia (AML) [1].
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BCR-ABL-IN-7
T72958688050-42-2
BCR-ABL-IN-7 is a WT and T315I mutant ABL kinase inhibitor.BCR-ABL-IN-7 potently inhibits WT and T315I mutant ABL kinase activity.BCR-ABL-IN-7 can be used in chronic myelogenous leukemia (CML) research.
- $30
Size
QTY
BCR-ABL-IN-5
T633321795736-60-5
BCR-ABL-IN-5 is a Bcr-Abl (Breakpoint cluster region-Abelson) kinase inhibitor that acts on Bcr-AblWT (IC50: 0.014 μM) and Bcr-AblT3151 (IC50: 0.45 μM) and exhibits some anti-proliferative effects on leukemic cells. effect.
- $1,520
Size
QTY
BCR-ABL-IN-6
T634502499499-26-0
BCR-ABL-IN-6 (9h) is an imatinib derivative and a selective inhibitor of Bcr-Abl kinase, showing activity on Bcr-AblWT (IC50: 4.6 nM) and Bcr-AblT3151 (IC50: 277 nM). BCR-ABL-IN-6 (9h) is utilized in studying chronic myeloid leukemia treatment.
- $1,520
Size
QTY
BCR-ABL-IN-8
T829091808288-49-4
BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor characterized by a trimethoxy group [1].
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Adaphostin
T22553241127-58-2
Adaphostin (NSC-680410) is a p210Bcr Abl tyrosine kinase inhibitor with IC50 of 14 μM.
- $64
Size
QTY
Tyrphostin AG 568
T24912151013-48-8
Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.
- $1,520
Size
QTY
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