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Results for "
pd126055
" in TargetMol Product Catalog- Inhibitors & Agonists2
Olodanrigan
PD-126055,EMA401
T44311316755-16-4
Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. EMA401 blocks p38, p42/p44 mitogen-activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons induced by AngII. It inhibits capsaicin responses in cultured hDRG neurons.
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Olodanrigan sodium
PD-126055,EMA401,EMA 401,EMA401 sodium,EMA-401,PD 126055
T282331316755-17-5
Olodanrigan is a novel orally available and highly selective antagonist of angiotensin II type 2 receptor (AT2R).
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