peg4-sulfonic acid

PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Carboxy-PEG4-sulfonic acid is a PEG-based linker commonly employed in PROTAC synthesis [1].

m-PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG4-sulfonic acid is a PEG4-based linker compound utilized in PROTAC synthesis[1].

Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- (4-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]butanoic acid) is a Cereblon ligand with alkyl linker and terminal acid for onward chemistry.

4-Methyl-4-(methyldisulfanyl)pentanoic acid is an ADC linker employed in the synthesis of antibody-drug conjugates (ADCs) that can be cleaved.

4-(N-Boc-amino)-1,6-heptanedioic acid is an alkyl/ether-based linker, suitable for PROTAC synthesis [1].

4-Bromobutylphosphonic acid is an alkyl chain-derived PROTAC linker employed for the synthesis of PROTACs[1].

Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkylC8 linker with terminal acid ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

m-PEG5-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Hydroxy-PEG2-C2-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-sulfonic acid is a polyethylene glycol (PEG) derived linker used for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Boc-PEG2-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Bis-PEG3-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

(4-Oxo-4H-quinazolin-3-yl)-acetic acid is an alkyl chain-derived PROTAC linker suitable for the synthesis of PROTACs[1].

4-Boc-amino-22-dimethylbutyric acid is an alkyl/ether-derived PROTAC linker, suitable for the synthesis of PROTACs.

Azido-PEG2-C2-sulfonic acid is a polyethylene glycol (PEG) derived linker compound employed for the synthesis of proteolysis-targeting chimeras (PROTACs) [1].

Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker utilized for the synthesis of PROTACs [1].

4-Maleimidobutyric acid is an alkyl chain-derived PROTAC linker that enables the synthesis of PROTACs[1].

Butoxycarbonyl-PEG5-sulfonic acid is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].

Phenyl-glutarimide 4'-oxyacetic acid, a carboxylic acid-functionalized cerebellar ligand, is utilized in developing PROTAC deactivators due to its superior hydrolytic stability and efficacy. This compound exhibits enhanced binding to PROTAC, [1].

Carboxy-PEG2-sulfonic acid is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Carboxy-PEG5-sulfonic acid, a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].

4-Methyl-4-(pyridin-2-yldisulfanyl)pentanoic acid is a cleavable linker compound employed in the synthesis of antibody-drug conjugates (ADCs)[1].