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By Target- LRRK2
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Results for "
pf 06447475
" in TargetMol Product Catalog- Inhibitors & Agonists3
PF-06447475
T20501527473-33-1
PF-06447475 is a highly effective, specific, brain penetrant LRRK2 inhibitor with IC0 of 3 11 nM for wild type LRRK2 and G2019S LRRK2 respectively.
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PF-06456384 trihydrochloride
T738461834610-75-1
PF-06447475 trihydrochloride is a potent, selective LRRK2 kinase inhibitor that demonstrates excellent brain penetration, exhibiting IC50 values of 3 nM for wild-type LRRK2 and 11 nM for G2019S LRRK2 variants. It holds potential for Parkinson's disease (PD) research [1].
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