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Results for "
pf-8380
" in TargetMol Product Catalog- Inhibitors & Agonists2
PF-8380
T36311144035-53-9
PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood). It modulates lysophosphatidic acid (LPA) levels in vivo/vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at the site of inflammation.
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PF-8380 hydrochloride
T635752070015-01-7
PF-8380 hydrochloride is a powerful inhibitor of autotaxin, exhibiting an IC(50) of 2.8 nM in isolated enzyme assays and 101 nM in human whole blood.
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