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Inhibitors & Agonists

pft beta

" in TargetMol Product Catalog

Inhibitors & Agonists
2

Pifithrin-β hydrobromide

T3637511296-88-1

Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM).

Ferroptosis p53

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Pifithrin-β

T2315660477-34-1

potent p53 inhibitor

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$1,520

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