preq1-dihydrochloride

Preq1-Dihydrochloride (pre-queuosine1 Dihydrochloride) is an intermediate of the queuosine pathway, it binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression.

RN-1 dihydrochloride is an effective and selective irreversible inhibitor of lysine-specific demethylase 1 (LSD1, IC50 = 70 nM).

Raf inhibitor 1 dihydrochloride (B-Raf inhibitor 1 dihydrochloride) is a potent and selective B-Raf inhibitor.

1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer's disease patients as well as those with hypersomnia and other neurological conditions.

TLR7/8 agonist 1 dihydrochloride (TLR7/8 agonist-5d) is a TLR7/8 agonist which shows prominent immunostimulatory activities.

SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunit SMARCA2 and is used for degrading SMARCA2 based on PROTAC.

LMPTP Inhibitor 1 Dihydrochloride is a compound selectively targeting low molecular weight protein tyrosine phosphatase (LMPTP), exhibiting potent inhibitory activity with an IC50 value of 0.8 μM for LMPTP-A.

11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65682 and the CAS number is 111974-74-4.

2-(2-(4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethoxy)ethanol dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T67203 and the CAS number is 1535-17-7.

(3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66079 and the CAS number is 1062580-52-2.

(3S,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T65526 and the CAS number is 1354486-07-9.

Chroman 1 dihydrochloride is a selective and potent inhibitor of ROCK, acting more strongly on ROCK2 (IC50: 1 pM) than ROCK1 (IC50: 52 pM) and also inhibiting MRCK activity (IC50: 150 nM).

Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM. It effectively inhibits the activity of Mps1 mitotic kinase and disrupts spindle assembly checkpoint (SAC) function, thereby reducing the viability of both cancerous and 'normal' cells.

DNA Crosslinker 1 (dihydrochloride) serves as a potent binder for the DNA minor groove, exhibiting a DNA binding affinity (ΔTm) of 1.1°C. This compound is utilized in research focused on anticancer therapies [1].

2-(4-((4-Chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethanol dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T64940 and the CAS number is 164726-80-1.

NUCC-390 dihydrochloride is selective agonist of small-molecule CXCR4 receptor.

1-Benzyl-4-methyl-3-(methylamino)piperidine dihydrochloride is a useful organic compound for research related to life sciences. The catalog number is T66156 and the CAS number is 1228879-37-5.

DDR1-IN-1 dihydrochloride is a selective and potent inhibitor of the DDR1 receptor tyrosine kinase, exhibiting an IC50 of 105 nM, and it demonstrates fourfold reduced potency against DDR2, with an IC50 of 413 nM.

2-(1-Methyl-1H-imidazol-4-yl)ethan-1-amine is a histamine metabolite.