propargyl peg4 ch2cooh

Propargyl-PEG4-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Cl-C6-PEG4-O-CH2COOH (PROTAC Linker 4) is an efficient pegylated PROTAC linker commonly used in the synthesis of chloroanes (HaloPROTACs).

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

Thalidomide-PEG4-Propargyl (Thalidomide-O-PEG4-Propargyl) is a synthetic E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker which can be used in PROTAC technology[1].

Amine-PEG-CH2COOH (MW 5000) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Cl-C6-PEG4-C3-COOH, a PROTAC linker, is a suitable component for synthesizing chloroalkane-containing PROTACs (HaloPROTACs).

1,1,1-Trifluoroethyl-PEG4-propargyl is a polyethylene glycol (PEG)-based linker used in the synthesis of PROTACs [1].

Thiol-PEG-CH2COOH (MW 5000) is a polyethylene glycol (PEG) derivative frequently used in the construction of PROTACs, bifunctional compounds designed for targeted protein degradation [1].

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a PEG-based PROTAC linker, assisting in the synthesis of PROTACs[1].

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.

Propargyl-PEG4-amine, a PEG-based PROTAC linker, can be used in the synthesis of PROTACs.

Ald-Ph-amido-PEG4-propargyl is a non-cleavable, 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker used in ADC synthesis[1].

Propargyl-PEG4-Br is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-NH-PEG4-CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Amine-PEG-CH2COOH (MW 3400) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs).

Amino-PEG4-CH2COOH is a PEG-based PROTAC linker and a non-cleavable 4-unit PEG ADC linker used in the synthesis of PROTACs and antibody-drug conjugates (ADCs).

Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis[1].

Boc-aminooxy-amide-PEG4-propargyl is a non-cleavable 4-unit polyethylene glycol (PEG) linker commonly used in the synthesis of antibody-drug conjugates (ADCs)[1].

m-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker suitable for synthesizing PROTACs[1].

Aminooxy-amido-PEG4-propargyl is a 4-unit PEG ADC linker, non-cleavable and specifically designed for the synthesis of antibody-drug conjugates (ADCs) [1].

Propargyl-PEG4-Sulfone-PEG4-acid serves as a PEG-based PROTAC linker for the synthesis of PROTACs[1].

Desthiobiotin-PEG4-propargyl is a PEG-coupled PROteolysis TArgeting Chimeric (PROTAC) linker used in PROTAC synthesis.

Amine-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG) derivative used as a linker in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Thalidomide-NH-PEG4-COOH is a conjugate comprising an E3 ligase ligand-linker, utilized in the synthesis of dCBP-1. dCBP-1 itself functions as a powerful and selective heterobifunctional degrader targeting p300 CBP.

Propargyl-PEG4-S-PEG4-acid, a polyethylene glycol (PEG)-based PROTAC linker, is suitable for synthesizing Proteolysis Targeting Chimera (PROTACs) [1].

Mal- PEG4- propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Tos-PEG4-CH2COOH is a PEG-based linker used in PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Boc-N-Amido-PEG4-propargyl is a PEG-based PROTAC linker used in the synthesis of PROTACs [1].

Propargyl-PEG4-S-PEG4-Boc is a polyethylene glycol (PEG) based linker designed for PROTAC synthesis [1].

S-acetyl-PEG4-propargyl is a PEG-based PROTAC linker used for synthesizing PROTACs [1].

N-methyl-N'-methyl-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker commonly used in synthesizing proteolysis-targeting chimeras (PROTACs) [1].

N-PEG3-N'-(propargyl-PEG4)-Cy5 is a polyethylene glycol (PEG)-derived linker used in the fabrication of proteolysis-targeting chimeras (PROTACs)[1].

Thiol-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker used for the synthesis of PROTACs[1].

Mal-amido-(CH2COOH)2, also known as compound 7a, is an intermediate compound that contains maleimidoethyl for use in hydrophilic ADC linker synthesis[1].

Propargyl-PEG4-thiol is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N,N'-bis-(propargyl-PEG4)-Cy5 (chloride) is a polyethylene glycol (PEG) based PROTAC linker used for synthesizing PROTACs[1].

Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker used in PROTAC synthesis [1].

Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl ether-based non-cleavable ADC linker. Propargyl-PEG5-Boc can be used to synthesize ADC inhibitors of Galectin-3[1].

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate that combines a Thalidomide-based cereblon ligand and a linker, commonly utilized in PROTAC technology. This compound serves as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

m-PEG4-CH2COOH is a PEG-based linker for PROTACs that combines two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

DSPE-PEG-CH2COOH (MW 2000) is a polyethylene glycol (PEG)-based linker molecule specifically designed for synthesizing protein-targeting chimeras (PROTACs)[1].

Aminooxy-PEG4-propargyl is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

HOOCCH2O-PEG4-CH2COOH (compound 5), is a symmetric polyethylene glycol (PEG) linker. It is primarily utilized in the synthesis of the initial Homo-PROTAC[1] compound.

Hydroxy-PEG4-CH2COOH is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the [ubiquitin-proteasome system] within cells.