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Results for "
psbkd477
" in TargetMol Product Catalog- Inhibitors & Agonists2
PSB-KD477
T696122488763-19-3
PSB-KD477 is an Agonist of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18. PSB-KD477 displayed significantly higher potency and efficacy than THC, determined in a GPR18-dependent β-arrestin recruitment assay, and were found to be selective versus the CB-sensitive receptors CB1, CB2, and GPR55. Structure-activity relationships were steep, and indole substitution was crucial for biological activity. These first selective agonists, which are structurally distinct from the lipidic agonist(s), will allow target validation studies and may eventually contribute to the deorphanization of GPR18.
- $1,520
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R-(+)-EU-1180-453
T696112488764-06-1In house
R-(+)-EU-1180-453 is a useful organic compound for research related to life sciences. The catalog number is T69611 and the CAS number is 2488764-06-1.
- $1,970
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