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  • Thyroid hormone receptor(THR)
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qrx431

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  • Inhibitors & Agonists
    3
    TargetMol | Activity
Sobetirome
IACS-010759,GC1,QRX-431,GC-1,GC 1
T5313211110-63-3
Sobetirome (IACS-010759) is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
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IACS-010759 hydrochloride
IACS-010759 HCl,IACS-010759,IACS10759,IACS-10759,IACS 10759
T275681807523-99-4
IACS-010759 is a potent inhibitor of complex I of OXPHOS with orally bioavailable. IACS-10759 effectively inhibits ATP production and oxygen consumption in isolated mitochondria, and inhibits the conversion of NADH to NAD+ in immunoprecipitated complex I
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7-10 days
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IACS-010759
IACS-10759,IACS 10759,IACS10759
T53371570496-34-2
IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.
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