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Results for "
r 115777
" in TargetMol Product Catalog- Inhibitors & Agonists3
R 115777
R115777,R-115777
T26012192185-68-5
R 115777 is an inhibitor of farnesyl transferase.
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Tipifarnib (S enantiomer)
Tipifarnib S enantiomer,(S)-(-)-R-115777,(S)-Tipifarnib,IND-58359 S enantiomer
T17102192185-71-0
Tipifarnib S enantiomer ((S)-(-)-R-115777) is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase inhibitor (IC50: 0.6 nM).
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Tipifarnib
R115777,Zarnestra,IND 58359
T6271192185-72-1
Tipifarnib (IND 58359) is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the enzyme farnesyl protein transferase, an enzyme involved in protein processing (farnesylation) for signal transduction. By inhibiting the farnesylation of proteins, this agent prevents the activation of Ras oncogenes, inhibits cell growth, induces apoptosis, and inhibits angiogenesis.
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