r-1485 dihydrochloride

5-HT6 antagonist,selective and high affinity

(S,R,S)-AHPC-PEG2-NH2 dihydrochloride (VH032-linker 12) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker[1].

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 9 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

(S,R,S)-AHPC-C4-NH2 dihydrochloride is a chemically derived E3 ligase ligand-linker conjugate that includes the (S,R,S)-AHPC VHL ligand and a linker specifically engineered for EED-Targeted PROTAC[1].

(R)-Methyl 2,6-diaminohexanoate dihydrochloride, catalog number T66306 and CAS number 67396-08-1, is a valuable organic compound for life sciences research.

R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor.

(S,R,S)-AHPC-C2-NH2 dihydrochloride, a combination of a VHL ligand for the E3 ubiquitin ligase and a PROTAC linker, facilitates the synthesis of various PROTACs.

(2R,2'R)-Di-tert-butyl 3,3'-disulfanediylbis(2-aminopropanoate) dihydrochloride is a valuable organic compound for life sciences research, catalog number T67000, CAS number 38261-78-8.

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a short alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 1 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

(S,R,S)-AHPC-Me dihydrochloride, also known as VHL ligand 2 dihydrochloride, is a chemical compound used in the synthesis of ARV-771. ARV-771 is a BET PROTAC degrader that relies on von Hippel-Landau (VHL) E3 ligase and exhibits potent degradation of BET proteins in castration-resistant prostate cancer (CRPC) cells, with a DC50 of less than 1 nM. This compound acts as the VHL ligand, specifically the (S,R,S)-AHPC-based VHL ligand, facilitating the recruitment of von Hippel-Lindau (VHL) protein.

Functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 phenol - linker 2 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was VH 032 - linker 11 PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

cdk/CK1 inhibitor,potent and ATP-competitive

(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along with a linker, which is used for the degradation of AKT PROTAC.

(S,R,S)-AHPC-C10-NH2 dihydrochloride (VH032-linker 10) is a synthesized E3 ligase ligand-linker conjugate, incorporating an (S,R,S)-AHPC-based VHL ligand and a linker[1].