rac desethyl oxybutynin (hydrochloride)

rac-Desethyl oxybutynin is an active metabolite of the muscarinic acetylcholine receptor (mAChR) antagonist oxybutynin .1,2,3rac-Desethyl oxybutynin is formed from oxybutynin by the cytochrome P450 (CYP) isoform CYP3A4.2It binds to mAChRs in isolated rat bladder, submaxillary gland, heart, and colon with Kivalues of 5.38, 3.12, 16, and 5.59 nM, respectively.rac-Desethyl oxybutynin (0.4 and 0.8 mg/kg) reduces micturition pressure in rats.3

N-Desethyl Chloroquine Hydrochloride ((±)-Desethylchloroquine 2HCl) is a desethylchloroquine derivative. desethylchloroquine competitively inhibits cyp2d1 /6-mediated reactions in vitro and in vivo.

rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol). It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).

rac Desmethyl Citalopram Hydrochloride is a 5-hydroxy tryptamine uptake inhibitor with IC50 value of 0.013 μM.

rac threo-Dihydro Bupropion-d9 Hydrochloride is a deuterated compound of rac threo-Dihydro Bupropion Hydrochloride. rac threo-Dihydro Bupropion Hydrochloride has a CAS number of 1396889-62-5.

(Rac)-IBT6A hydrochloride is a racemic mixture of IBT6A hydrochloride, an impurity of Ibrutinib, involved in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct [1]. IBT6A is related to Ibrutinib, a selective and irreversible Bruton's tyrosine kinase (Btk) inhibitor with an IC50 of 0.5 nM [2].

N-Desethyl Sunitinib hydrochloride (SU-12662 hydrochloride) is an active metabolite of Sunitinib with potential anti-cancer activity for the study of cancer.

(Rac)-IBT6A hydrochloride is a racemate of IBT6A. IBT6A is an impurity of Ibrutinib. IBT6A can be used in the synthesis of IBT6A Ibrutinib dimer and IBT6A adduct. Ibrutinib is a Btk inhibitor (IC50: 0.5 nM).

rac NorMetanephrine-d3 Hydrochloride is a deuterated compound of rac NorMetanephrine Hydrochloride.

rac-Paroxetine-d4 Hydrochloride is a deuterated compound of rac-Paroxetine Hydrochloride. rac-Paroxetine Hydrochloride has a CAS number of 78246-49-8. Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.

rac Atomoxetine-d5 Hydrochloride is a deuterated compound of rac Atomoxetine Hydrochloride. rac Atomoxetine Hydrochloride has a CAS number of 82857-40-7.

(Rac)-Atomoxetine D7 hydrochloride is a deuterium labeled (Rac)-Atomoxetine hydrochloride. (Rac)-Atomoxetine hydrochloride is a racemic form of Atomoxetine hydrochloride.

rac Metanephrine-d3 Hydrochloride Salt is a deuterated compound of rac Metanephrine Hydrochloride Salt.

Di-N-desethyl Amiodarone hydrochloride, a metabolite of Amiodarone, functions as a potent inhibitor of the respiratory chain [1].

(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine, a full agonist of the dopamine receptor and a partial agonist of the 5-HT1A receptor.

(Rac)-5-Hydroxymethyl Tolterodine hydrochloride, also known as (Rac)-Desfesoterodine hydrochloride, is an active metabolite of Tolterodine that functions as a mAChR antagonist. It exhibits significant affinity (K i values) for M1, M2, M3, M4, and M5 receptors, with values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM, respectively. This compound is commonly employed in research related to overactive bladder conditions.

(Rac)-CP-601927 hydrochloride is the racemate form of CP-601927, a nicotinic acetylcholine receptor (nAChR) agonist, with Ki values of 1.2 nM for α4β2 and 102 nM for α3β4 nAChR.

N-Desethyl Oxybutynin D5 hydrochloride is the the active metabolite Oxybutynin, is deuterium labeled N-Desethyl Oxybutynin hydrochloride.